Interim analysis of an open-label randomized controlled trial evaluating nasal irrigations in non-hospitalized patients with coronavirus disease 2019

被引:30
|
作者
Kimura, Kyle S. [1 ]
Freeman, Michael H. [1 ]
Wessinger, Bronson C. [2 ]
Gupta, Veerain [2 ]
Sheng, Quanhu [3 ]
Huang, Li Ching [3 ]
Von Wahlde, Kate [1 ]
Das, Suman R. [1 ,4 ]
Chowdhury, Naweed I. [1 ]
Turner, Justin H. [1 ]
机构
[1] Vanderbilt Univ, Med Ctr, Dept Otolaryngol Head & Neck Surg, 1215 21st Ave South,Suite 7209, Nashville, TN 37232 USA
[2] Vanderbilt Univ, Sch Med, Nashville, TN 37212 USA
[3] Vanderbilt Univ, Med Ctr, Dept Biostat, Nashville, TN USA
[4] Vanderbilt Univ, Sch Med, Dept Med, Div Microbiol & Infect Dis, Nashville, TN 37212 USA
关键词
saline; coronavirus; COVID-19; irrigation; nasal;
D O I
10.1002/alr.22703
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
引用
收藏
页码:1325 / 1328
页数:4
相关论文
共 50 条
  • [41] Oseltamivir for coronavirus illness: post-hoc exploratory analysis of an open-label, pragmatic, randomised controlled trial in European primary care from 2016 to 2018
    Coenen, Samuel
    van Der Velden, Alike W.
    Cianci, Daniela
    Goossens, Herman
    Bongard, Emily
    Saville, Benjamin R.
    Gobat, Nina
    de Paor, Muireann
    Leven, Margareta
    Verheij, Theo J.
    Butler, Christopher C.
    BRITISH JOURNAL OF GENERAL PRACTICE, 2020, 70 (696) : E444 - E449
  • [42] Efficacy and safety of Levamisole treatment in clinical presentations of non-hospitalized patients with COVID-19: a double-blind, randomized, controlled trial
    Amirreza Roostaei Firozabad
    Zohreh Akhoundi Meybodi
    Seyed Ruhollah Mousavinasab
    Adeleh Sahebnasagh
    Mohsen Gholinataj Jelodar
    Iman Karimzadeh
    Solomon Habtemariam
    Fatemeh Saghafi
    BMC Infectious Diseases, 21
  • [43] Efficacy and safety of Levamisole treatment in clinical presentations of non-hospitalized patients with COVID-19: a double-blind, randomized, controlled trial
    Firozabad, Amirreza Roostaei
    Meybodi, Zohreh Akhoundi
    Mousavinasab, Seyed Ruhollah
    Sahebnasagh, Adeleh
    Jelodar, Mohsen Gholinataj
    Karimzadeh, Iman
    Habtemariam, Solomon
    Saghafi, Fatemeh
    BMC INFECTIOUS DISEASES, 2021, 21 (01)
  • [44] Cardiac Adverse Events and Remdesivir in Hospitalized Patients With Coronavirus Disease 2019 (COVID-19): A Post Hoc Safety Analysis of the Randomized DisCoVeRy Trial
    Terzic, Vida
    Basilua, Joe Miantezila
    Billard, Nicolas
    de Gastines, Lucie
    Belhadi, Drifa
    Fougerou-Leurent, Claire
    Peiffer-Smadja, Nathan
    Mercier, Noemie
    Delmas, Christelle
    Ferrane, Assia
    Dechanet, Aline
    Poissy, Julien
    Esperou, Helene
    Ader, Florence
    Hites, Maya
    Andrejak, Claire
    Greil, Richard
    Paiva, Jose-Artur
    Staub, Therese
    Tacconelli, Evelina
    Burdet, Charles
    Costagliola, Dominique
    Mentre, France
    Yazdanpanah, Yazdan
    Diallo, Alpha
    CLINICAL INFECTIOUS DISEASES, 2024, 79 (02) : 382 - 391
  • [45] Favipiravir and Hydroxychloroquine Combination Therapy in Patients with Moderate to Severe COVID-19 (FACCT Trial): An Open-Label, Multicenter, Randomized, Controlled Trial
    Mohammad Bosaeed
    Ebrahim Mahmoud
    Ahmad Alharbi
    Hadeel Altayib
    Hawra Albayat
    Faisal Alharbi
    Khalid Ghalilah
    Abdulmajid Al Arfaj
    Jumana AlJishi
    Abdullatif Alarfaj
    Hajar Alqahtani
    Badriah M. Almutairi
    Manar Almaghaslah
    Nawaf M. Alyahya
    Abdullah Bawazir
    Saud AlEisa
    Abdulrahman Alsaedy
    Abderrezak Bouchama
    Malak Alharbi
    Majid AlShamrani
    Sameera Al Johani
    Majed Aljeraisy
    Mohammed Alzahrani
    Abdulhakeem O. Althaqafi
    Hassan Almarhabi
    Athari Alotaibi
    Nasser Alqahtani
    Yaseen M. Arabi
    Omar S. Aldibasi
    Ahmad Alaskar
    Infectious Diseases and Therapy, 2021, 10 : 2291 - 2307
  • [46] Evaluation of convalescent plasma versus standard of care for the treatment of COVID-19 in hospitalized patients: study protocol for a phase 2 randomized, open-label, controlled, multicenter trial
    Diago-Sempere, Elena
    Bueno, Jose Luis
    Sancho-Lopez, Aranzazu
    Rubio, Elena Munez
    Torres, Ferran
    de Molina, Rosa Malo
    Fernandez-Cruz, Ana
    de Diego, Isabel Salcedo
    Velasco-Iglesias, Ana
    Payares-Herrera, Concepcion
    Flecha, Inmaculada Casas
    Avendano-Sola, Cristina
    Palomino, Rafael Duarte
    Ramos-Martinez, Antonio
    Ruiz-Antoran, Belen
    TRIALS, 2021, 22 (01)
  • [47] Favipiravir and Hydroxychloroquine Combination Therapy in Patients with Moderate to Severe COVID-19 (FACCT Trial): An Open-Label, Multicenter, Randomized, Controlled Trial
    Bosaeed, Mohammad
    Mahmoud, Ebrahim
    Alharbi, Ahmad
    Altayib, Hadeel
    Albayat, Hawra
    Alharbi, Faisal
    Ghalilah, Khalid
    Al Arfaj, Abdulmajid
    AlJishi, Jumana
    Alarfaj, Abdullatif
    Alqahtani, Hajar
    Almutairi, Badriah M.
    Almaghaslah, Manar
    Alyahya, Nawaf M.
    Bawazir, Abdullah
    AlEisa, Saud
    Alsaedy, Abdulrahman
    Bouchama, Abderrezak
    Alharbi, Malak
    AlShamrani, Majid
    Al Johani, Sameera
    Aljeraisy, Majed
    Alzahrani, Mohammed
    Althaqafi, Abdulhakeem O.
    Almarhabi, Hassan
    Alotaibi, Athari
    Alqahtani, Nasser
    Arabi, Yaseen M.
    Aldibasi, Omar S.
    Alaskar, Ahmad
    INFECTIOUS DISEASES AND THERAPY, 2021, 10 (04) : 2291 - 2307
  • [48] Favipiravir in Patients With Early Mild-to-moderate Coronavirus Disease 2019 (COVID-19): A Randomized Controlled Trial
    Golan, Yoav
    Campos, Jesus Abraham Simon
    Woolson, Rob
    Cilla, Donald
    Hanabergh, Rodolfo
    Gonzales-Rojas, Yaneicy
    Lopez, Reynaldo
    Finberg, Robert
    Balboni, Armand
    CLINICAL INFECTIOUS DISEASES, 2023, 76 (03) : E10 - E17
  • [49] OR32. Efficacy and Safety of Therapeutic Versus Prophylactic Dose of Anticoagulation in Hospitalized Patients with Severe COVID-19 Pneumonia and Coagulopathy: An Open-Label, Randomized Controlled Trial
    Adrian, L. H.
    Hutomo, S. A.
    Negari, A. D. S.
    EUROPEAN HEART JOURNAL SUPPLEMENTS, 2021, 23 (SUPPL F)
  • [50] Colchicine and/or Naltrexone for Hospitalized COVID-19 Patients Not Requiring High Levels of Ventilatory Support (COLTREXONE): A Prospective, Randomized, Open-Label Trial
    Gertner, Elie
    Schullo-Feulner, Anne
    Knutson, Alison
    Chrenka, Ella
    O'Brien, Meghan
    Behrendt, Christine
    Johnson, Joseph
    Delaney, Daniel
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2024, 16 (05)