CELL SIGNALLING Nutrient sensing lost in cancer

被引:9
作者
Menon, Suchithra [1 ]
Manning, Brendan D. [1 ]
机构
[1] Harvard Univ, Sch Publ Hlth, Dept Genet & Complex Dis, Boston, MA 02115 USA
关键词
DEPRIVATION; COMPLEX; MTORC1;
D O I
10.1038/498444a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
[No abstract available]
引用
收藏
页码:444 / 445
页数:2
相关论文
共 50 条
  • [21] Do signalling endosomes play a role in T cell activation?
    Benzing, Carola
    Rossy, Jeremie
    Gaus, Katharina
    [J]. FEBS JOURNAL, 2013, 280 (21) : 5164 - 5176
  • [22] Distribution of T-cell signalling molecules in human myeloma
    Bianchi, A
    Mariani, S
    Beggiato, E
    Borrione, P
    Peola, S
    Boccadoro, M
    Pileri, A
    Massaia, M
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 1997, 97 (04) : 815 - 820
  • [23] mTOR signalling pathway in stem cell bioactivities and angiogenesis potential
    Lotfimehr, Hamid
    Mardi, Narges
    Narimani, Samaneh
    Nasrabadi, Hamid Tayefi
    Karimipour, Mohammad
    Sokullu, Emel
    Rahbarghazi, Reza
    [J]. CELL PROLIFERATION, 2023, 56 (12)
  • [24] T cell receptor signalling networks: branched, diversified and bounded
    Brownlie, Rebecca J.
    Zamoyska, Rose
    [J]. NATURE REVIEWS IMMUNOLOGY, 2013, 13 (04) : 257 - 269
  • [25] p62 Is a Key Regulator of Nutrient Sensing in the mTORC1 Pathway
    Duran, Angeles
    Amanchy, Ramars
    Linares, Juan F.
    Joshi, Jayashree
    Abu-Baker, Shadi
    Porollo, Aleksey
    Hansen, Malene
    Moscat, Jorge
    Diaz-Meco, Maria T.
    [J]. MOLECULAR CELL, 2011, 44 (01) : 134 - 146
  • [26] Identification of Novel AR-Targeted MicroRNAs Mediating Androgen Signalling through Critical Pathways to Regulate Cell Viability in Prostate Cancer
    Mo, Wenjuan
    Zhang, Jiyuan
    Li, Xia
    Meng, Delong
    Gao, Yun
    Yang, Shu
    Wan, Xuechao
    Zhou, Caihong
    Guo, Fenghua
    Huang, Yan
    Amente, Stefano
    Avvedimento, Enrico V.
    Xie, Yi
    Li, Yao
    [J]. PLOS ONE, 2013, 8 (02):
  • [27] Intestinal region-specific Wnt signalling profiles reveal interrelation between cell identity and oncogenic pathway activity in cancer development
    Adam, Ronja S.
    van Neerven, Sanne M.
    Pleguezuelos-Manzano, Cayetano
    Simmini, Salvatore
    Leveille, Nicolas
    de Groot, Nina E.
    Holding, Andrew N.
    Markowetz, Florian
    Vermeulen, Louis
    [J]. CANCER CELL INTERNATIONAL, 2020, 20 (01)
  • [28] Disruption of lysosomal nutrient sensing scaffold contributes to pathogenesis of a fatal neurodegenerative lysosomal storage disease
    Bagh, Maria B.
    Appu, Abhilash P.
    Sadhukhan, Tamal
    Mondal, Avisek
    Plavelil, Nisha
    Raghavankutty, Mahadevan
    Supran, Ajayan M.
    Sadhukhan, Sriparna
    Liu, Aiyi
    Mukherjee, Anil B.
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2024, 300 (02)
  • [29] MDM4 actively restrains cytoplasmic mTORC1 by sensing nutrient availability
    Mancini, Francesca
    Teveroni, Emanuela
    Di Conza, Giusy
    Monteleone, Valentina
    Arisi, Ivan
    Pellegrino, Marsha
    Buttarelli, Marianna
    Pieroni, Luisa
    D'Onofrio, Mara
    Urbani, Andrea
    Pontecorvi, Alfredo
    Mazzone, Massimiliano
    Moretti, Fabiola
    [J]. MOLECULAR CANCER, 2017, 16
  • [30] Nutrient inputs and social metabolic control of T cell fate
    Bacigalupa, Zachary A.
    Landis, Madelyn D.
    Rathmell, Jeffrey C.
    [J]. CELL METABOLISM, 2024, 36 (01) : 10 - 20