Logic and justification for dimensional assessment of symptoms and related clinical phenomena in psychosis: Relevance to DSM-5

被引:137
作者
Barch, Deanna M. [1 ,2 ,3 ]
Bustillo, Juan [4 ]
Gaebel, Wolfgang [5 ]
Gur, Raquel [6 ,7 ,8 ]
Heckers, Stephan [9 ]
Malaspina, Dolores [10 ,11 ]
Owen, Michael J. [12 ,13 ]
Schultz, Susan [14 ]
Tandon, Rajiv [15 ]
Tsuang, Ming [16 ,17 ,18 ,19 ,20 ]
Van Os, Jim [21 ,22 ]
Carpenter, William [23 ]
机构
[1] Washington Univ, Dept Psychol, St Louis, MO 63130 USA
[2] Washington Univ, Dept Psychiat, St Louis, MO 63130 USA
[3] Washington Univ, Dept Radiol, St Louis, MO 63130 USA
[4] Univ New Mexico, Dept Psychiat, Albuquerque, NM 87131 USA
[5] Univ Dusseldorf, Fac Med, Dept Psychiat & Psychotherapy, D-40225 Dusseldorf, Germany
[6] Univ Penn, Dept Psychiat, Perlman Sch Med, Philadelphia, PA 19104 USA
[7] Univ Penn, Dept Neurol, Perlman Sch Med, Philadelphia, PA 19104 USA
[8] Univ Penn, Dept Radiol, Perlman Sch Med, Philadelphia, PA 19104 USA
[9] Vanderbilt Univ, Dept Psychiat, Nashville, TN 37235 USA
[10] NYU, Dept Psychiat, New York, NY 10016 USA
[11] Creedmoor Psychiat Ctr, New York State Off Mental Hlth, Queens, NY USA
[12] Cardiff Univ, MRC Ctr Neuropsychiat Genet, Cardiff CF10 3AX, S Glam, Wales
[13] Cardiff Univ, Neurosci & Mental Hlth Res Inst, Cardiff CF10 3AX, S Glam, Wales
[14] Univ Iowa, Sch Med, Dept Psychiat, Iowa City, IA 52242 USA
[15] Univ Florida, Dept Psychiat, Sch Med, Gainesville, FL 32611 USA
[16] Univ Calif San Diego, Ctr Behav Genom, San Diego, CA 92103 USA
[17] Univ Calif San Diego, Dept Psychiat, San Diego, CA 92103 USA
[18] Univ Calif San Diego, Inst Genom Med, San Diego, CA 92103 USA
[19] Vet Affairs San Diego Hlth Care Syst, San Diego, CA USA
[20] Harvard Univ, Sch Publ Hlth, Harvard Inst Psychiat Epidemiol & Genet, Boston, MA 02115 USA
[21] Maastricht Univ Med Ctr, South Limburg Mental Hlth Res & Teaching Network, EURON, Maastricht, Netherlands
[22] Kings Coll London, Kings Hlth Partners, Dept Psychosis Studies, Inst Psychiat, London, England
[23] Maryland Psychiat Res Ctr, Dept Psychiat, Baltimore, MD 21228 USA
基金
英国医学研究理事会;
关键词
Psychosis; Diagnosis; DSM-5; Schizoaffective; Dimensions; Cognition; BRIEF COGNITIVE ASSESSMENT; NEGATIVE SYMPTOMS; BIPOLAR DISORDER; SCHIZOPHRENIA-PATIENTS; NEUROCOGNITIVE DEFICITS; FUNCTIONAL-CAPACITY; FLAT AFFECT; NEUROPSYCHOLOGICAL PERFORMANCE; 1ST-EPISODE SCHIZOPHRENIA; SCHIZOAFFECTIVE DISORDER;
D O I
10.1016/j.schres.2013.04.027
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Work on the causes and treatment of schizophrenia and other psychotic disorders has long recognized the heterogeneity of the symptoms that can be displayed by individuals with these illnesses. Further, researchers have increasingly emphasized the ways in which the severity of different symptoms of this illness can vary across individuals, and have provided evidence that the severity of such symptoms can predict other important aspects of the illness, such as the degree of cognitive and/or neurobiological deficits. Additionally, research has increasingly emphasized that the boundaries between nosological entities may not be categorical and that the comorbidity of disorders may reflect impairments in common dimensions of genetic variation, human behavior and neurobiological function. As such, it is critical to focus on a dimensional approach to the assessment of symptoms and clinically relevant phenomena in psychosis, so as to increase attention to and understanding of the causes and consequences of such variation. In the current article, we review the logic and justification for including dimensional assessment of clinical symptoms in the evaluation of psychosis in the Fifth Edition of the Diagnostic and Statistical Manual for Mental Disorders (DSM-5). (C) 2013 Elsevier B. V. All rights reserved.
引用
收藏
页码:15 / 20
页数:6
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