Recent findings of green tea extract AR25 (Exolise) and its activity for the treatment of obesity

被引：209
作者：
Chantre, P
Lairon, D
机构：
[1] Arkopharma Labs, F-06511 Carros, France
[2] INSERM, Unit 476, F-13258 Marseille, France
来源：
PHYTOMEDICINE | 2002年 / 9卷 / 01期
关键词：
green tea extract; gastric and pancreatic lipase; thermogenesis; obesity; catechins;
D O I：
10.1078/0944-7113-00078
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The green tea extract AR25 is an 80 % ethanolic dry extract standardized at 25 % catechins expressed as epigallocatechin gallate (EGCG). In vitro, green tea extract AR25 exerts a direct inhibition of gastric and pancreatic lipases and a stimulation of thermogenesis. In an open study, the effects of extract AR25 were evaluated in moderately obese patients. After 3 months, body weight was decreased by 4.6 % and waist circumference by 4.48 %. These results suggest the green tea extract AR25 to be a natural product for the treatment of obesity, which exerts its activity by several ways: inhibition of lipases and stimulation of thermogenesis.
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页码：3 / 8
页数：6
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