Spectroscopic studies of micelle-enhanced ligand exchange of gallium (III)/4-(2-pyridylazo) resorcinol complex by calf thymus DNA

被引：1

作者：

Romeika, Jennifer M. ^{[1
]}

Spurgeon, Charina L. ^{[1
]}

Yan, Fei ^{[1
]}

机构：

[1] N Carolina Cent Univ, Dept Chem, Durham, NC 27707 USA

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2014年 / 117卷

基金：

美国国家科学基金会;

关键词：

Gallium; CTAB; PAR; dsDNA; ssDNA; Micelle; IN-VITRO BINDING; WATER; GA-67;

D O I：

10.1016/j.saa.2013.07.113

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

The effect of cationic micelles of cetyltrimethylammonium bromide (CTAB) on the interaction of gallium (III) with 4-(2-pyridylazo) resorcinol (PAR) under varying conditions has been studied spectrophotometrically. At pH 6.0, CTAB (0.05% w/v) markedly enhanced the absorption intensity of gallium (III)-PAR complex. Furthermore, the introduction of CTAB provided unique selectivity for the ligand exchange of Ga(III)-PAR by calf thymus dsDNA over calf thymus ssDNA. This phenomenon offers a novel spectrophotometric sensing strategy for direct detection of dsDNA. (C) 2013 Elsevier B.V. All rights reserved.

引用

页码：120 / 126

页数：7

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