ABO blood group: old dogma, new perspectives

被引:82
作者
Franchini, Massimo [1 ]
Liumbruno, Giancarlo Maria [2 ,3 ,4 ]
机构
[1] Azienda Osped Carlo Poma, Dept Transfus Med & Hematol, Mantua, Italy
[2] AFAR, San Giovanni Calibita Fatebenefratelli Hosp, Immunohematol Unit, Rome, Italy
[3] AFAR, San Giovanni Calibita Fatebenefratelli Hosp, Transfus Med Unit, Rome, Italy
[4] AFAR, San Giovanni Calibita Fatebenefratelli Hosp, Clin Pathol Unit, Rome, Italy
关键词
ABO blood group; cancer; cardiovascular disorders; thrombosis; von Willebrand factor; VON-WILLEBRAND-FACTOR; PANCREATIC-CANCER; HELICOBACTER-PYLORI; GASTRIC-CANCER; GROUP ANTIGENS; FACTOR-VIII; GROUP-A; GROUP-O; RISK; TRANSFUSION;
D O I
10.1515/cclm-2013-0168
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Human blood group antigens are glycoproteins and glycolipids expressed on the surface of red blood cells and a variety of human tissues, including the epithelium, sensory neurons, platelets and the vascular endothelium. Accumulating evidence indicate that ABO blood type is implicated in the development of a number of human diseases, including cardiovascular and neoplastic disorders. In this review, beside its physiologic role in immunohematology and transfusion medicine, we summarize the current knowledge on the association between the ABO blood group and the risk of developing thrombotic events and cancers.
引用
收藏
页码:1545 / 1553
页数:9
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