Summary of Meeting Proceedings on Addressing Variability around the Cut Point in Serial Interferon-γ Release Assay Testing

被引:18
作者
Daley, Charles L. [1 ,2 ]
Reves, Randall R. [2 ,3 ]
Beard, Melodie A. [4 ]
Boyle, Jeffrey [5 ]
Clark, Richard B. [6 ]
Beebe, James L. [7 ]
Catanzaro, Antonino [8 ]
Chen, Lisa [9 ,10 ]
Desmond, Edward [11 ]
Dorman, Susan E. [12 ]
Hudson, T. Warner [13 ,14 ]
Lardizabal, Alfred A. [15 ,16 ]
Kapoor, Hema [17 ]
Marder, David C. [18 ,19 ]
Miranda, Cyndee [20 ]
Narita, Masahiro [21 ,22 ]
Reichman, Lee [15 ]
Schwab, Dale [23 ]
Seaworth, Barbara J. [24 ,25 ]
Terpeluk, Paul [26 ]
Thanassi, Wendy [27 ,28 ]
Kawamura, L. Masae [29 ]
机构
[1] Natl Jewish Hlth, Dept Med, Denver, CO USA
[2] Univ Colorado Denver, Dept Med, Aurora, CO USA
[3] Denver Publ Hlth Dept, Denver Metro TB Control Program, Denver, CO USA
[4] Lab Corp Amer Holdings, Burlington, NC USA
[5] Cellestis QIAGEN, Dept Res & Dev, Melbourne, Vic, Australia
[6] Quest Diagnost Nichols Inst, Chantilly, VA USA
[7] San Luis Obispo Cty Publ Hlth Lab, San Luis Obispo, CA USA
[8] Univ Calif San Diego, Dept Med, San Diego, CA 92103 USA
[9] Curry Int TB Ctr, San Francisco, CA USA
[10] Univ Calif San Francisco, Dept Med, San Francisco, CA USA
[11] Calif Dept Publ Hlth, Microbial Dis Lab, Richmond, CA USA
[12] Johns Hopkins Univ, Sch Med, Baltimore, MD USA
[13] Univ Calif Los Angeles, Los Angeles, CA USA
[14] Amer Coll Occupat & Environm Med, Elk Grove Village, IL USA
[15] Univ Med & Dent New Jersey, New Jersey Med Sch, Global TB Inst, Newark, NJ 07103 USA
[16] Univ Med & Dent New Jersey, Dept Med, Newark, NJ 07103 USA
[17] Quest Diagnost, Horsham, PA USA
[18] UIC, Univ Hlth Serv, Chicago, IL USA
[19] UIC, Chicago, IL USA
[20] Dept Infect Dis, Cleveland Clin, Cleveland, OH 44106 USA
[21] Seattle King Cty Dept Publ Hlth, Seattle, WA USA
[22] Univ Washington, Div Pulm & Crit Care Med, Seattle, WA 98195 USA
[23] Quest Diagnost Nichols Inst, San Juan Capistrano, CA USA
[24] Heartland Natl TB Ctr, Austin, TX USA
[25] Univ Texas Hlth Sci Ctr, Dept Med, Tyler, TX USA
[26] Employee Hlth Serv, Cleveland Clin, Cleveland, OH 44106 USA
[27] Dept Vet Affairs, Palo Alto, CA USA
[28] Stanford Univ, Dept Emergency Med, Stanford, CA 94305 USA
[29] Cellestis QIAGEN, Dept Res & Dev, Valencia, CA USA
关键词
HEALTH-CARE WORKERS; WITHIN-SUBJECT VARIABILITY; TUBERCULOSIS INFECTION; LATENT TUBERCULOSIS; CONVERSIONS;
D O I
10.1086/670635
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
On June 13, 2012, a group of key stakeholders, leaders, and national experts on tuberculosis (TB), occupational health, and laboratory science met in Atlanta, Georgia, to focus national discussion on the higher than expected positive results occurring among low-risk, unexposed healthcare workers undergoing serial testing with interferon-g release assays (IGRAs). The objectives of the meeting were to present the latest clinical and operational research findings on the topic, to discuss evaluation and treatment algorithms that are emerging in the absence of national guidance, and to develop a consensus on the action steps needed to assist programs and physicians in the interpretation of serial testing IGRA results. This report summarizes its proceedings.
引用
收藏
页码:625 / 630
页数:6
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