Chemical characterisation and biological effects of Juniperus foetidissima Willd. 1806

被引：48
作者：
Lesjak, Marija M. [1 ]
Beara, Ivana N. [1 ]
Orcic, Dejan Z. [1 ]
Ristic, Jelena D. [1 ]
Anackov, Goran T. [2 ]
Bozin, Biljana N. [3 ]
Mimica-Dukic, Neda M. [1 ]
机构：
[1] Univ Novi Sad, Fac Sci, Dept Chem Biochem & Environm Protect, Novi Sad 21000, Serbia
[2] Univ Novi Sad, Fac Sci, Dept Biol & Ecol, Novi Sad 21000, Serbia
[3] Univ Novi Sad, Fac Med, Dept Pharm, Novi Sad 21000, Serbia
来源：
LWT-FOOD SCIENCE AND TECHNOLOGY | 2013年 / 53卷 / 02期
关键词：
Juniperus foetidissima; GC-MS; LC-MS/MS; Anti-inflammatory activity; Antioxidant activity; ESSENTIAL OILS; ANTIOXIDANT ACTIVITIES; POLYPHENOLS; BERRIES; LEAVES; FRUITS; PLANTS; L;
D O I：
10.1016/j.lwt.2013.03.010
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
The present study was designed to define the phenolic and terpene profile, antioxidant and anti-inflammatory activity of methanol extracts and essential oils of the leaves and seed cones of funiperus foetidissima species, on which there has been little previous research. The content of 44 phenolics in extracts was determined using LC-MS/MS. A comparable qualitative composition, including dominant compounds catechin, quercitrin, epicatechin, rutin and quercetin-3-O-glucoside, was found in both extracts. GC MS analysis showed a simple terpene composition, with monoterpenes dominant and sabinene most abundant compound, 39.9% in leaves and 29.9% in seed cones. Antioxidant activity was determined by several assays. All results of antioxidant tests were comparable to BHT, a well-known synthetic antioxidant. A novel method for estimation of anti-inflammatory potential by means of inhibition of COX-1 and 12-LOX activity was described. Essential oils showed significant anti-inflammatory activity, especially of leaves. To conclude, J. foetidissima showed great bio potential, and its usage in production of food and beverages should be considered. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码：530 / 539
页数：10
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