Installing Multiple Functional Groups on Biodegradable Polyesters via Post-Polymerization Olefin Cross-Metathesis

被引：28

作者：

Sinclair, Fern ^{[1
]}

Chen, Long ^{[2
]}

Greenland, Barnaby W. ^{[2
]}

Shaver, Michael P. ^{[1
]}

机构：

[1] Univ Edinburgh, EastCHEM Sch Chem, Joseph Black Bldg,David Brewster Rd, Edinburgh EH9 3FJ, Midlothian, Scotland

[2] Univ Reading, Reading Sch Pharm, Reading RG6 6AP, Berks, England

来源：

MACROMOLECULES | 2016年 / 49卷 / 18期

关键词：

RING-OPENING POLYMERIZATION; BETA-BUTYROLACTONE; ALUMINUM SALEN; EPOXIDE CARBONYLATION; TRIBLOCK COPOLYMERS; LACTONES; CATALYSTS; LACTIDE; SELECTIVITY; DENDRIMERS;

D O I：

10.1021/acs.macromol.6b01571

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Olefin cross-metathesis is an effective tool for the functionalization of biodegradable aliphatic polyesters through both pre- and post-polymerization of beta-heptenolactone (beta HL). Ring-opening polymerization of beta HL accesses both homopolymers and novel copolymers, producing strong gradient copolymers with lactide. A total of 15 different alkene cross-partners ranging from type I to type III olefins are readily incorporated to produce polyesters with a range of functionalities, altering the thermal and chemical properties of the resulting polymers. A novel methodology was also developed to introduce two unique functionalities into the polymer backbone based on manipulation of cross-partner reactivity, showcasing the scope and versatility of olefin CM as a strategy for post-polymerization modification of polymers.

引用

页码：6826 / 6834

页数：9

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