SYNTHESIS OF β-LACTAMS FROM ACIDS AND IMINES USING THIOCARBONYLDIIMIDAZOLE

被引：26

作者：

Zarei, Maaroof ^{[1
]}

Karimi-Jaberi, Zahed ^{[2
]}

Movahedi, Amin ^{[2
]}

机构：

[1] Hormozgan Univ, Dept Chem, Coll Sci, Bandar Abbas 71961, Iran

[2] Islamic Azad Univ, Dept Chem, Firoozabad Branch, Firoozabad, Fars, Iran

来源：

SYNTHETIC COMMUNICATIONS | 2013年 / 43卷 / 05期

关键词：

2-Azetidinones; ketene; beta-lactams; Staudinger reaction; thiocarbonyldiimidazole; SOLID-PHASE SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; VILSMEIER REAGENT; HUMAN-LEUKOCYTE; DERIVATIVES; RING; AZETIDIN-2-ONES; INHIBITORS; EZETIMIBE; MECHANISM;

D O I：

10.1080/00397911.2011.607935

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Thiocarbonyldiimidazole has been found to be an efficient acid activator for the synthesis of beta-lactams by ketene-imine cycloaddition at room temperature. The experimental procedure is simple and results in excellent yields of the products. All products were characterized by spectral data and elemental analyses.

引用

页码：728 / 734

页数：7

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