SYNTHESIS OF β-LACTAMS FROM ACIDS AND IMINES USING THIOCARBONYLDIIMIDAZOLE

被引：26
作者：
Zarei, Maaroof [1 ]
Karimi-Jaberi, Zahed [2 ]
Movahedi, Amin [2 ]
机构：
[1] Hormozgan Univ, Dept Chem, Coll Sci, Bandar Abbas 71961, Iran
[2] Islamic Azad Univ, Dept Chem, Firoozabad Branch, Firoozabad, Fars, Iran
来源：
SYNTHETIC COMMUNICATIONS | 2013年 / 43卷 / 05期
关键词：
2-Azetidinones; ketene; beta-lactams; Staudinger reaction; thiocarbonyldiimidazole; SOLID-PHASE SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; VILSMEIER REAGENT; HUMAN-LEUKOCYTE; DERIVATIVES; RING; AZETIDIN-2-ONES; INHIBITORS; EZETIMIBE; MECHANISM;
D O I：
10.1080/00397911.2011.607935
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Thiocarbonyldiimidazole has been found to be an efficient acid activator for the synthesis of beta-lactams by ketene-imine cycloaddition at room temperature. The experimental procedure is simple and results in excellent yields of the products. All products were characterized by spectral data and elemental analyses.
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页码：728 / 734
页数：7
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