Molecular biology - Managing associations between different chromosomes

被引:11
作者
Spilianakis, CG [1 ]
Flavell, RA [1 ]
机构
[1] Yale Univ, Sch Med, Immunobiol Sect, New Haven, CT 06520 USA
关键词
D O I
10.1126/science.1126689
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Genes present on different chromosomes can be coordinately expressed through a transcription regulatory factor that brings them together in a region of active transcription in the nucleus.
引用
收藏
页码:207 / 208
页数:2
相关论文
共 9 条
  • [1] Bacher CP, 2006, NAT CELL BIOL, V8, P293, DOI 10.1038/ncb1365
  • [2] Coregulated human globin genes are frequently in spatial proximity when active
    Brown, JM
    Leach, J
    Reittie, JE
    Atzberger, A
    Lee-Prudhoe, J
    Wood, WG
    Higgs, DR
    Iborra, FJ
    Buckle, VJ
    [J]. JOURNAL OF CELL BIOLOGY, 2006, 172 (02) : 177 - 187
  • [3] Chromatin conversations: Mechanisms and implications of paramutation
    Chandler, VL
    Stam, M
    [J]. NATURE REVIEWS GENETICS, 2004, 5 (07) : 532 - 544
  • [4] Capturing chromosome conformation
    Dekker, J
    Rippe, K
    Dekker, M
    Kleckner, N
    [J]. SCIENCE, 2002, 295 (5558) : 1306 - 1311
  • [5] CTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf1
    Ling, JQ
    Li, T
    Hu, JF
    Vu, TH
    Chen, HL
    Qiu, XW
    Cherry, AM
    Hoffman, AR
    [J]. SCIENCE, 2006, 312 (5771) : 269 - 272
  • [6] The dynamics of chromosome organization and gene regulation
    Spector, DL
    [J]. ANNUAL REVIEW OF BIOCHEMISTRY, 2003, 72 : 573 - 608
  • [7] Interchromosomal associations between alternatively expressed loci
    Spilianakis, CG
    Lalioti, MD
    Town, T
    Lee, GR
    Flavell, RA
    [J]. NATURE, 2005, 435 (7042) : 637 - 645
  • [8] Looping and interaction between hypersensitive sites in the active β-globin locus
    Tolhuis, B
    Palstra, RJ
    Splinter, E
    Grosveld, F
    de Laat, W
    [J]. MOLECULAR CELL, 2002, 10 (06) : 1453 - 1465
  • [9] Transient homologous chromosome pairing marks the onset of X inactivation
    Xu, N
    Tsai, CL
    Lee, JT
    [J]. SCIENCE, 2006, 311 (5764) : 1149 - 1152