Hyaluronic acid based scaffolds for tissue engineering-A review

被引:828
|
作者
Collins, Maurice N. [1 ]
Birkinshaw, Colin [2 ]
机构
[1] Univ Limerick, Stokes Res Inst, Limerick, Ireland
[2] Univ Limerick, Dept Mat Sci & Technol, Limerick, Ireland
关键词
Hyaluronic acid; Tissue engineering; Scaffolds; IN-SITU; HYBRID SCAFFOLDS; INTRAUTERINE ADHESIONS; POROUS SCAFFOLDS; HYDROGEL FILMS; CELL-ADHESION; CROSS-LINKING; BONE-MARROW; BROAD RANGE; STEM-CELLS;
D O I
10.1016/j.carbpol.2012.10.028
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
This review focuses on hyaluronic acid (HA) tissue scaffolding materials. Scaffolds are defined in terms of formation mechanisms and mode of action. Solution properties are discussed as an understanding of the hydrodynamics of HA is fundamental in optimising the subsequent modification and the chemistries behind important tissue engineering applications that are emerging from recent research on this increasingly valuable carbohydrate polymer are described. Key scaffold characteristics such as mechanical, biological function and degradation are discussed. The latest technologies behind scaffold processing are assessed and the applications of HA based scaffolds are discussed. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1262 / 1279
页数:18
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