Palladium-catalyzed cross-coupling reactions of coumarin derivatives: An overview

被引:27
作者
Kanchana, U. S. [1 ]
Diana, Elizabeth J. [1 ]
Mathew, Thomas, V [1 ]
Anilkumar, Gopinathan [2 ,3 ]
机构
[1] St Thomas Coll Pala, Dept Chem, Arunapuram PO, Kottayam 686574, Kerala, India
[2] Mahatma Gandhi Univ, Sch Chem Sci, P D Hills PO, Kottayam 686560, Kerala, India
[3] Mahatma Gandhi Univ, Inst Integrated Programmes & Res Basic Sci, Priyadarshini Hills PO, Kottayam 686560, Kerala, India
关键词
catalysis; C-C; coumarin; cross-coupling; palladium; SUZUKI-MIYAURA; 4-ARYLCOUMARIN ANALOGS; 4-SUBSTITUTED COUMARINS; OPTICAL-PROPERTIES; PART; ACIDS; HYDROARYLATION; ACCESS; 4-PHENYLCOUMARINS; COMBRETASTATINS;
D O I
10.1002/aoc.5983
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Coumarins are omnipresent in several plants and exhibit a plethora of pharmacological properties, making them an important scaffold in organic synthesis. Naturally, the chemistry of this motif has attracted ever-increasing attention, among which palladium-catalyzed coupling reactions are the most prevalent one. Numerous useful, easy, and concise syntheses and reactions have been achieved using palladium-catalyzed coupling reactions. This review focuses on recent advances in palladium-catalyzed cross-coupling reactions such as Suzuki, Heck, Stille, Sonogoshira etc. reactions of coumarin derivatives and covers the literature from 2001 to 2020.
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页数:17
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