Clarithromycin associated with torsades de pointes

被引:30
作者
Kamochi, H [1 ]
Nii, T [1 ]
Eguchi, K [1 ]
Mori, T [1 ]
Yamamoto, A [1 ]
Shimoda, K [1 ]
Ibaraki, K [1 ]
机构
[1] Karatsu Red Cross Hosp, Dept Internal Med, Saga 8478588, Japan
来源
JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION | 1999年 / 63卷 / 05期
关键词
clarithromycin; torsades de pointes;
D O I
10.1253/jcj.63.421
中图分类号
N09 [自然科学史]; B [哲学、宗教];
学科分类号
01 ; 0101 ; 010108 ; 060207 ; 060305 ; 0712 ;
摘要
Two cases of QT prolongation and torsades de pointes (TdP) are presented. The patients had been taking clarithromycin (400 mg/day) for respiratory disease. Although erythromycin is reportedly associated with TdP, this is the first report of clarithromycin associated with TdP in the absence of other drugs already known to produce QT prolongation.
引用
收藏
页码:421 / 422
页数:2
相关论文
共 8 条
[1]   Cellular and ionic mechanisms underlying erythromycin-induced long QT intervals and torsade de pointes [J].
Antzelevitch, C ;
Sun, ZQ ;
Zhang, ZQ ;
Yan, GX .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1996, 28 (07) :1836-1848
[2]   Erythromycin monotherapy associated with torsade de pointes [J].
Granberry, MC ;
Gardner, SF .
ANNALS OF PHARMACOTHERAPY, 1996, 30 (01) :77-78
[3]   THE LONG QT SYNDROMES - A CRITICAL-REVIEW, NEW CLINICAL OBSERVATIONS AND A UNIFYING HYPOTHESIS [J].
JACKMAN, WM ;
FRIDAY, KJ ;
ANDERSON, JL ;
ALIOT, EM ;
CLARK, M ;
LAZZARA, R .
PROGRESS IN CARDIOVASCULAR DISEASES, 1988, 31 (02) :115-172
[4]   ELECTROPHYSIOLOGICAL MECHANISMS IN A CANINE MODEL OF ERYTHROMYCIN-ASSOCIATED LONG QT SYNDROME [J].
RUBART, M ;
PRESSLER, ML ;
PRIDE, HP ;
ZIPES, DP .
CIRCULATION, 1993, 88 (04) :1832-1844
[5]   DIAGNOSTIC-CRITERIA FOR THE LONG QT SYNDROME - AN UPDATE [J].
SCHWARTZ, PJ ;
MOSS, AJ ;
VINCENT, GM ;
CRAMPTON, RS .
CIRCULATION, 1993, 88 (02) :782-784
[6]   Torsades de Pointes in two chronic renal failure patients treated with cisapride and clarithromycin [J].
Sekkarie, MA .
AMERICAN JOURNAL OF KIDNEY DISEASES, 1997, 30 (03) :437-439
[7]   PROBUCOL-INDUCED QT PROLONGATION AND SYNCOPE [J].
TAMURA, M ;
UEKI, Y ;
OHTSUKA, E ;
ORIBE, M ;
SEITA, M ;
ORIBE, K ;
ITO, M .
JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION, 1994, 58 (05) :374-377
[8]   Cisapride and fatal arrhythmia [J].
Wysowski, DK ;
Bacsanyi, J .
NEW ENGLAND JOURNAL OF MEDICINE, 1996, 335 (04) :290-291