Analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children

被引：8
作者：
Valenzise, Mariella [1 ]
Aversa, Tommaso [1 ]
Zirilli, Giuseppina [1 ]
Salzano, Giuseppina [1 ]
Corica, Domenico [1 ]
Santucci, Simona [1 ]
De Luca, Filippo [1 ]
机构：
[1] Univ Messina, Dept Human Pathol Adulthood & Childhood, Via Consolare Valeria, I-98125 Messina, Italy
来源：
ITALIAN JOURNAL OF PEDIATRICS | 2017年 / 43卷
关键词：
Chromosomopathies; Down's syndrome; Hashimoto's thyroiditis; Thyroid function; Thyroid status; Turner syndrome; AUTOIMMUNE THYROID-DISEASES; HASHIMOTOS-THYROIDITIS; DOWN-SYNDROME; NATURAL-HISTORY; FOLLOW-UP; TURNER; ADOLESCENTS; ASSOCIATION; WOMEN; GIRLS;
D O I：
10.1186/s13052-016-0322-z
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Aim of this commentary is to report the most recent views about natural history of subclinical hypothyroidism (SH) according to the different etiologies. In children with idiopathic SH the natural evolution is often favourable, with a high percentage of cases reverting to euthyroidism or remaining SH even after a prolonged follow-up. By contrast, the risk of a significant deterioration of thyroid status is distinctly higher in the SH children with Hashimoto's thyroiditis (HT). This risk is even higher in the cases with both HT-related SH and chromosomal abnormalities, such as Turner or Down's syndrome.
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页码：1 / 6
页数：6
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