The elucidation of the structure of the core part of the LPS from Plesiomonas shigelloides serotype O17 expressing O-polysaccharide chain identical to the Shigella sonnei O-chain

被引：19
作者：
Kubler-Kielb, Joanna [2 ]
Schneerson, Rachel [2 ]
Mocca, Chris [2 ]
Vinogradov, Evgeny [1 ]
机构：
[1] CNR, Inst Biol Sci, Ottawa, ON K1A 0R6, Canada
[2] NICHHD, NIH, Bethesda, MD 20892 USA
来源：
CARBOHYDRATE RESEARCH | 2008年 / 343卷 / 18期
关键词：
LPS; O-Chain; Plesiomonas shigelloides; Shigella sonnei; Conjugate vaccine; Structure; Core;
D O I：
10.1016/j.carres.2008.09.017
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Plesiomonas shigelloides O17 LPS contains the same O-antigenic polysaccharide chain as a causative agent of dysentery, Shigella sonnei. This polysaccharide can be used as a component of a vaccine against dysentery. Core part of the P. shigelloides O17 LPS was studied using NMR and mass spectrometry and the following structure was proposed: [GRAPHICS] Significant similarity of the P. shigelloides O17 LPS core with the structure of the P. shigelloides O54 core was observed. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码：3123 / 3127
页数：5
相关论文
共 11 条
[1]   Double-blind vaccine-controlled randomised efficacy trial of an investigational Shigella sonnei conjugate vaccine in young adults [J].
Cohen, D ;
Ashkenazi, S ;
Green, MS ;
Gdalevich, M ;
Robin, G ;
Slepon, R ;
Yavzori, M ;
Orr, N ;
Block, C ;
Ashkenazi, I ;
Shemer, J ;
Taylor, DN ;
Hale, TL ;
Sadoff, JC ;
Pavliakova, D ;
Schneerson, R ;
Robbins, JB .
LANCET, 1997, 349 (9046) :155-159
[2]   Plesiomonas shigelloides septicemia: Case report and literature review [J].
Lee, ACW ;
Yuen, KY ;
Ha, SY ;
Chiu, DCK ;
Lau, YL .
PEDIATRIC HEMATOLOGY AND ONCOLOGY, 1996, 13 (03) :265-269
[3]   Structure of the lipid A-inner core region and biological activity of Plesiomonas shigelloides O54 (strain CNCTC 113/92) lipopolysaccharide [J].
Lukasiewicz, Jolanta ;
Niedziela, Tomasz ;
Jachymek, Wojciech ;
Kenne, Lennart ;
Lugowski, Czeslaw .
GLYCOBIOLOGY, 2006, 16 (06) :538-550
[4]   Core oligosaccharides of Plesiomonas shigelloides O54:H2 (strain CNCTC 113/92) -: Structural and serological analysis of the lipopolysaccharide core region, the O-antigen biological repeating unit, and the linkage between them [J].
Niedziela, T ;
Lukasiewicz, J ;
Jachymek, W ;
Dzieciatkowska, M ;
Lugowski, C ;
Kenne, L .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (14) :11653-11663
[5]   PROTECTION FROM SHIGELLA-SONNEI INFECTION BY IMMUNIZATION OF RABBITS WITH PLESIOMONAS-SHIGELLOIDES (SVC 01) [J].
SAYEED, S ;
SACK, DA ;
QADRI, F .
JOURNAL OF MEDICAL MICROBIOLOGY, 1992, 37 (06) :382-384
[6]   Comparison of O-antigen gene clusters of Escherichia coli (Shigella) sonnei and Plesiomonas shigelloides O17:: Sonnei gained its current plasmid-borne O-antigen genes from P-shigelloides in a recent event [J].
Shepherd, JG ;
Wang, L ;
Reeves, PR .
INFECTION AND IMMUNITY, 2000, 68 (10) :6056-6061
[7]  
SZU S, 2004, NEW GENERATION VACCI, P471
[8]   SYNTHESIS, CHARACTERIZATION, AND CLINICAL-EVALUATION OF CONJUGATE VACCINES COMPOSED OF THE O-SPECIFIC POLYSACCHARIDES OF SHIGELLA-DYSENTERIAE TYPE-1, SHIGELLA-FLEXNERI TYPE-2A, AND SHIGELLA-SONNEI (PLESIOMONAS-SHIGELLOIDES) BOUND TO BACTERIAL TOXOIDS [J].
TAYLOR, DN ;
TROFA, AC ;
SADOFF, J ;
CHU, CY ;
BRYLA, D ;
SHILOACH, J ;
COHEN, D ;
ASHKENAZI, S ;
LERMAN, Y ;
EGAN, W ;
SCHNEERSON, R ;
ROBBINS, JB .
INFECTION AND IMMUNITY, 1993, 61 (09) :3678-3687
[9]   The structure of the rough-type lipopolysaccharide from Shewanella oneidensis MR-1, containing 8-amino-8-deoxy-Kdo and an open-chain form of 2-acetamido-2-deoxy-D-galactose [J].
Vinogradov, E ;
Korenevsky, A ;
Beveridge, TJ .
CARBOHYDRATE RESEARCH, 2003, 338 (19) :1991-1997
[10]   IDENTIFICATION OF SHIGELLA-SONNEI FORM-I PLASMID GENES NECESSARY FOR CELL INVASION AND THEIR CONSERVATION AMONG SHIGELLA SPECIES AND ENTEROINVASIVE ESCHERICHIA-COLI [J].
WATANABE, H ;
NAKAMURA, A .
INFECTION AND IMMUNITY, 1986, 53 (02) :352-358
12