Stereoselective synthesis of conjugated α-Z/γ-E and α-Z/γ-Z dienoic acids. Kinetic torquoselectivity versus thermodynamic control

被引：12

作者：

Agarwal, Jyoti ^{[1
]}

Bayounes, Ouahiba ^{[1
]}

Thorimbert, Serge ^{[1
]}

Dechoux, Luc ^{[1
]}

机构：

[1] Univ Paris 06, Inst Parisien Chim Mol, UMR CNRS 7201, F-75005 Paris, France

来源：

RSC ADVANCES | 2014年 / 4卷 / 06期

关键词：

DERIVATIVES; 2-PYRONES; PYRANE; DFT;

D O I：

10.1039/c3ra45309j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The stereoselective synthesis of conjugated (alpha-Z/gamma-E)-(alpha-Z/gamma-Z)-dienoic acids 4 and 4' is described. It is based on the regio- and stereoselective addition of Grignard reagents to methylcoumalate. The origin of the stereocontrol is discussed.

引用

页码：2772 / 2775

页数：4

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