The analysis of multivariate longitudinal data: A review

被引:211
作者
Verbeke, Geert [1 ,2 ]
Fieuws, Steffen [1 ]
Molenberghs, Geert [1 ,2 ]
Davidian, Marie [3 ]
机构
[1] Katholieke Univ Leuven, Interuniv Inst Biostat & Stat Bioinformat, B-3000 Louvain, Belgium
[2] Univ Hasselt, Interuniv Inst Biostat & Stat Bioinformat, B-3590 Diepenbeek, Belgium
[3] N Carolina State Univ, Dept Stat, Raleigh, NC 27695 USA
关键词
Mixed models; random effects; shared parameters; marginal models; conditional models; latent variables; ANALYZING DEVELOPMENTAL TRAJECTORIES; COMPOSITE LIKELIHOOD APPROACH; CORRELATED BINARY REGRESSION; RANDOM-EFFECTS MODELS; MIXED-EFFECTS MODELS; LATENT CURVE MODELS; COVARIANCE-STRUCTURES; HEARING THRESHOLDS; COMPONENT ANALYSIS; 3-MODE MODELS;
D O I
10.1177/0962280212445834
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Longitudinal experiments often involve multiple outcomes measured repeatedly within a set of study participants. While many questions can be answered by modeling the various outcomes separately, some questions can only be answered in a joint analysis of all of them. In this article, we will present a review of the many approaches proposed in the statistical literature. Four main model families will be presented, discussed and compared. Focus will be on presenting advantages and disadvantages of the different models rather than on the mathematical or computational details.
引用
收藏
页码:42 / 59
页数:18
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