Oxygen and wound care: A review of current therapeutic modalities and future direction

被引:69
作者
Howard, Michael A. [1 ]
Asmis, Reto [3 ]
Evans, Karen Kim [4 ]
Mustoe, Thomas A. [2 ]
机构
[1] Univ Chicago, Pritzker Sch Med, North Shore Univ HealthSyst, Northbrook, IL 60062 USA
[2] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA
[3] Univ Texas Hlth Sci Ctr San Antonio, San Antonio, TX 78229 USA
[4] Georgetown Univ Hosp, Washington, DC 20007 USA
关键词
ENDOTHELIAL GROWTH-FACTOR; HYPERBARIC-OXYGEN; TOPICAL OXYGEN; INSPIRED OXYGEN; TRANSDERMAL OXYGEN; FACTOR EXPRESSION; ULCERS; HYPEROXIA; GRADIENTS; PERFUSION;
D O I
10.1111/wrr.12069
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
While the importance of oxygen to the wound healing process is well accepted, research and technological advances continue in this field and efforts are ongoing to further utilize oxygen as a therapeutic modality. In this paper, the authors briefly review the role of oxygen in wound healing and discuss the distinct mechanism of action as well as the advantages and disadvantages of the three major oxygen-based therapies currently in clinical use (Hyperbaric Oxygen and Topical Oxygen and Continuous Diffusion of Oxygen), as well as review the existing literature regarding these distinct therapeutic modalities.
引用
收藏
页码:503 / 511
页数:9
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