Chronic Cough

被引:74
作者
Smith, Jaclyn A. [1 ]
Woodcock, Ashley [1 ]
机构
[1] Univ Manchester, Univ Hosp South Manchester, Manchester Acad Hlth Sci Ctr, Manchester, Lancs, England
关键词
GASTROESOPHAGEAL-REFLUX DISEASE; REFRACTORY CHRONIC COUGH; LARYNGOPHARYNGEAL REFLUX; CLINICAL-FEATURES; CHEST GUIDELINE; BILE-ACIDS; MANAGEMENT; DIAGNOSIS; THERAPY; MANIFESTATION;
D O I
10.1056/NEJMcp1414215
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 63-year-old woman presents with a 1-year history of a chronic dry cough, associated with a sensation of "irritation" in the throat. Prolonged bouts of coughing are associated with stress urinary incontinence and occasionally end with retching and vomiting. The cough is triggered by changes in temperature, strong smells (e.g., the smell of cleaning products), laughing, and prolonged talking. She has no notable medical history, reports being otherwise well, and does not smoke. She has been prescribed a bronchodilator and inhaled and nasal glucocorticoids, but has had no benefit from any of these. The results of a physical examination, chest radiography, and spirometry are normal. How would you further evaluate and manage this condition?
引用
收藏
页码:1544 / 1551
页数:8
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