Biocatalytic and Chemo-Enzymatic Approaches for the Synthesis of Heterocycles

被引：11

作者：

Zhao, Fei ^{[1
]}

Masci, Domiziana ^{[1
]}

Tomarelli, Elena ^{[1
]}

Castagnolo, Daniele ^{[1
]}

机构：

[1] Kings Coll London, Sch Canc & Pharmaceut Sci, 150 Stamford St, London SE1 9NH, England

来源：

SYNTHESIS-STUTTGART | 2020年 / 52卷 / 20期

关键词：

heterocycles; biocatalysis; chemo-enzymatic cascades; green chemistry; heteroaromatic; ONE-POT CASCADE; C-H AMINATION; ALCOHOL-DEHYDROGENASE; EPSILON-CAPROLACTONE; ASYMMETRIC-SYNTHESIS; BUILDING-BLOCKS; ENZYME CASCADES; IN-VITRO; MAO-N; OXIDATION;

D O I：

10.1055/s-0040-1707210

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Heterocycles are ubiquitous structures in nature and can be found in many drugs and chemicals. Biocatalysts, alone or in combination with other metal catalysts, can be exploited for the construction of various heterocyclic rings under mild reaction conditions. This Short Review highlights the recent advances in the development of biocatalytic and chemo-enzymatic methods for the synthesis of both aliphatic and aromatic heterocyclic rings.

引用

页码：2948 / 2961

页数：14

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