Inhibition of Mcl-1 Enhances the Efficacy of Tyrosine Kinase Inhibition in FLT3 Mutated AML and Synergizes with Venetoclax Targeting AML Stem Cells

被引：0

作者：

Carter, Bing Z. ^{[1
]}

Tao, Wenjing ^{[1
]}

Mak, Po Yee ^{[1
]}

Zhang, Qi ^{[2
]}

Wang, Xiangmeng ^{[1
]}

Kuruvilla, Vinitha Mary ^{[3
]}

Stewart, Carli ^{[2
]}

Ruvolo, Vivian ^{[1
]}

Battula, Venkata Lokesh ^{[1
]}

Konopleva, Marina Y. ^{[1
]}

Caenepeel, Sean ^{[4
]}

Canon, Jude ^{[4
]}

Hughes, Paul ^{[4
]}

Morrow, P. K. ^{[4
]}

Andreeff, Michael ^{[1
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Sect Mol Hematol & Therapy, Dept Leukemia, Houston, TX 77030 USA

[2] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA

[3] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Houston, TX 77030 USA

[4] Amgen Inc, Thousand Oaks, CA 91320 USA

来源：

BLOOD | 2019年 / 134卷

关键词：

D O I：

10.1182/blood-2019-125725

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

1267

引用

页数：4

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