Inhibition of Mcl-1 Enhances the Efficacy of Tyrosine Kinase Inhibition in FLT3 Mutated AML and Synergizes with Venetoclax Targeting AML Stem Cells

被引:0
作者
Carter, Bing Z. [1 ]
Tao, Wenjing [1 ]
Mak, Po Yee [1 ]
Zhang, Qi [2 ]
Wang, Xiangmeng [1 ]
Kuruvilla, Vinitha Mary [3 ]
Stewart, Carli [2 ]
Ruvolo, Vivian [1 ]
Battula, Venkata Lokesh [1 ]
Konopleva, Marina Y. [1 ]
Caenepeel, Sean [4 ]
Canon, Jude [4 ]
Hughes, Paul [4 ]
Morrow, P. K. [4 ]
Andreeff, Michael [1 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Sect Mol Hematol & Therapy, Dept Leukemia, Houston, TX 77030 USA
[2] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
[3] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Houston, TX 77030 USA
[4] Amgen Inc, Thousand Oaks, CA 91320 USA
关键词
D O I
10.1182/blood-2019-125725
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1267
引用
收藏
页数:4
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