Whole Exome Sequencing Reveals Multiple Driver Events in Chronic Lymphocytic Leukemia Patients with Acquired Ibrutinib Resistance

被引：0
|
作者：
Underbayev, Chingiz [1 ]
Ahn, Inhye E. [1 ]
Harris, Hailey [1 ]
Vaughn, Lauren T. [1 ]
Pirooznia, Mehdi [2 ]
Xi, Liqiang [3 ]
Raffeld, Mark [3 ]
Herman, Sarah E. M. [1 ]
Wiestner, Adrian [1 ]
机构：
[1] NHLBI, Hematol Branch, NIH, Bethesda, MD 20892 USA
[2] NHLBI, Bioinformat & Computat Biol Core, Div Intramural Res, NIH, Bldg 10, Bethesda, MD 20892 USA
[3] NCI, Pathol Lab, NIH, Bethesda, MD 20892 USA
来源：
BLOOD | 2019年 / 134卷
关键词：
D O I：
10.1182/blood-2019-127364
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页数：3
相关论文
共 50 条
  • [1] Selinexor is effective in acquired resistance to ibrutinib and synergizes with ibrutinib in chronic lymphocytic leukemia
    Hing, Zachary A.
    Mantel, Rose
    Beckwith, Kyle A.
    Guinn, Daphne
    Williams, Erich
    Smith, Lisa L.
    Williams, Katie
    Johnson, Amy J.
    Lehman, Amy M.
    Byrd, John C.
    Woyach, Jennifer A.
    Lapalombella, Rosa
    BLOOD, 2015, 125 (20) : 3128 - 3132
  • [2] Genomic Landscape of Chinese Patients with Chronic Lymphocytic Leukemia By Whole-Exome Sequencing
    Miao, Yi
    Xia, Yi
    Qiao, Chun
    Zhu, Huayuan
    Wu, Jiazhu
    Jin, Hui
    Fu, Jianxin
    Wang, Li
    Fan, Lei
    Xu, Wei
    Li, Jianyong
    BLOOD, 2019, 134
  • [3] Genomic landscape of Chinese patients with chronic lymphocytic leukemia by whole-exome sequencing
    Miao, Yi
    Xia, Yi
    Qiao, Chun
    Zhu, Hua-Yuan
    Wu, Jia-Zhu
    Jin, Hui
    Fu, Jian-Xin
    Wang, Li
    Fan, Lei
    Xu, Wei
    Li, Jianyong
    LEUKEMIA & LYMPHOMA, 2020, 61 : 24 - 26
  • [4] Ibrutinib Resistance in Chronic Lymphocytic Leukemia
    Furman, Richard R.
    Cheng, Shuhua
    Lu, Pin
    Setty, Menu
    Perez, Alexendar R.
    Guo, Ailin
    Racchumi, Joelle
    Xu, Guozhou
    Wu, Hao
    Ma, Jiao
    Steggerda, Susanne M.
    Coleman, Morton
    Leslie, Christina
    Wang, Y. Lynn
    NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (24): : 2352 - 2354
  • [5] Whole Exome Sequencing of Chronic Myeloid Leukemia Patients
    Sabri, Shaghayegh
    Keyhani, Manouchehr
    Akbari, Mohammad Taghi
    IRANIAN JOURNAL OF PUBLIC HEALTH, 2016, 45 (03) : 346 - 352
  • [6] Cardiovascular Adverse Events Associated with Ibrutinib in Chronic Lymphocytic Leukemia Patients
    George, Binsah
    Thompson, Philip A.
    Ferrajoli, Alessandria
    Burger, Jan A.
    Wierda, William G.
    O'Brien, Susan M.
    Durand, Jean-Bernard
    Keating, Michael J.
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2015, 15 : S208 - S208
  • [7] Overcoming Ibrutinib Resistance in Chronic Lymphocytic Leukemia
    Pula, Bartosz
    Golos, Aleksandra
    Gorniak, Patryk
    Jamroziak, Krzysztof
    CANCERS, 2019, 11 (12)
  • [8] Deciphering Ibrutinib Resistance in Chronic Lymphocytic Leukemia
    Lenz, Georg
    JOURNAL OF CLINICAL ONCOLOGY, 2017, 35 (13) : 1451 - +
  • [9] Whole-exome and whole-genome sequencing in chronic lymphocytic leukemia: new biomarkers to target
    Hobeika, Charbel
    Rached, Gaelle
    Chebly, Alain
    Chouery, Eliane
    Kourie, Hampig Raphael
    PHARMACOGENOMICS, 2020, 21 (13) : 957 - 962
  • [10] Ibrutinib in Treatment of Patients with chronic lymphocytic Leukemia
    Flammiger, A.
    ONKOLOGE, 2015, 21 (08): : 732 - 733
12345