Cystosarcoma phyllodes of the breast

被引:0
|
作者
Kobayashi, T [1 ]
Asakawa, H [1 ]
Komoike, Y [1 ]
Nakano, Y [1 ]
Tamaki, Y [1 ]
Monden, M [1 ]
机构
[1] OSAKA UNIV, SCH MED, DEPT INTERNAL MED 2, SUITA, OSAKA 565, JAPAN
关键词
cystosarcoma phyllodes; multivariate analysis; recurrence; histopathology; disease-free interval; and breast-conserving surgery;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Forty-nine patients with cystosarcoma phyllodes (CP), aged 13-81 years, (mean 35.2 years) were studied. Tumor size ranged from 1.9 to 14 cm (mean 5.2 cm). Mean follow-up period was 11.3 years. Tumors were histopathologically graded as benign, borderline or malignant. Forty-two tumors were diagnosed as benign; 4 borderline and 3 malignant. Six patients had recurrent disease within 6 years of their first surgery. Statistical analysis showed that age was not a significant factor for predicting recurrence or malignant histopathology. Five patients with relapse had borderline or malignant tumors larger than 4 cm. The histopathologic diagnosis was concordant with the clinical course. Multivariate analysis showed that tumor size and histology were significant and independent factors for disease-free interval. Breast-conserving surgery with a wide tumor-free margin is preferred in CP, and close follow-up is advised in cases with malignant or borderline histopathology and tumors larger than 4 cm.
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页码:123 / 125
页数:3
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