Chromatin Configuration Affects the Dynamics and Distribution of a Transiently Interacting Protein

被引:20
作者
Amitai, Assaf [1 ,2 ]
机构
[1] MIT, Dept Chem Engn, Inst Med Engn & Sci, Cambridge, MA 02139 USA
[2] Ragon Inst MGH MIT & Harvard, Cambridge, MA 02139 USA
关键词
DNA-BINDING PROTEINS; FACILITATED DIFFUSION; MAMMALIAN-CELLS; SINGLE-MOLECULE; GENE-REGULATION; LIVING CELLS; IN-VIVO; SEARCH; KINETICS; VISUALIZATION;
D O I
10.1016/j.bpj.2017.12.037
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
[No abstract available]
引用
收藏
页码:766 / 771
页数:6
相关论文
共 41 条
[1]   Polymer physics of nuclear organization and function [J].
Amitai, A. ;
Holcman, D. .
PHYSICS REPORTS-REVIEW SECTION OF PHYSICS LETTERS, 2017, 678 :1-83
[2]   Diffusing Polymers in Confined Microdomains and Estimation of Chromosomal Territory Sizes from Chromosome Capture Data [J].
Amitai, A. ;
Holcman, D. .
PHYSICAL REVIEW LETTERS, 2013, 110 (24)
[3]   Visualization of Chromatin Decompaction and Break Site Extrusion as Predicted by Statistical Polymer Modeling of Single-Locus Trajectories [J].
Amitai, Assaf ;
Seeber, Andrew ;
Gasser, Susan M. ;
Holcman, David .
CELL REPORTS, 2017, 18 (05) :1200-1214
[4]  
[Anonymous], 1981, A Second Course in Stochastic Processes
[5]   Generalized Facilitated Diffusion Model for DNA-Binding Proteins with Search and Recognition States [J].
Bauer, Maximilian ;
Metzler, Ralf .
BIOPHYSICAL JOURNAL, 2012, 102 (10) :2321-2330
[6]   Facilitated Diffusion of Proteins on Chromatin [J].
Benichou, O. ;
Chevalier, C. ;
Meyer, B. ;
Voituriez, R. .
PHYSICAL REVIEW LETTERS, 2011, 106 (03)
[7]   Searching Fast for a Target on DNA without Falling to Traps [J].
Benichou, O. ;
Kafri, Y. ;
Sheinman, M. ;
Voituriez, R. .
PHYSICAL REVIEW LETTERS, 2009, 103 (13)
[8]   DIFFUSION-DRIVEN MECHANISMS OF PROTEIN TRANSLOCATION ON NUCLEIC-ACIDS .1. MODELS AND THEORY [J].
BERG, OG ;
WINTER, RB ;
VONHIPPEL, PH .
BIOCHEMISTRY, 1981, 20 (24) :6929-6948
[9]   Single molecule study of non-specific binding kinetics of Lacl in mammalian cells [J].
Caccianini, Laura ;
Normanno, Davide ;
Izeddin, Ignacio ;
Dahan, Maxime .
FARADAY DISCUSSIONS, 2015, 184 :393-400
[10]   Facilitated diffusion framework for transcription factor search with conformational changes [J].
Cartailler, Jorome ;
Reingruber, Juergen .
PHYSICAL BIOLOGY, 2015, 12 (04)