Genetic association mapping and genome organization of maize

被引：720
作者：
Yu, JM
Buckler, ES [1 ]
机构：
[1] Cornell Univ, Inst Genom Divers, Ithaca, NY 14853 USA
[2] Cornell Univ, USDA, Agr Res Serv, Ithaca, NY 14853 USA
[3] Cornell Univ, Dept Plant Breeding & Genet, Ithaca, NY 14853 USA
来源：
CURRENT OPINION IN BIOTECHNOLOGY | 2006年 / 17卷 / 02期
基金：
美国国家科学基金会; 美国农业部;
关键词：
D O I：
10.1016/j.copbio.2006.02.003
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Association mapping, a high-resolution method for mapping quantitative trait loci based on linkage disequilibrium, holds great promise for the dissection of complex genetic traits. The recent assembly and characterization of maize association mapping panels, development of improved statistical methods, and successful association of candidate genes have begun to realize the power of candidate-gene association mapping. Although the complexity of the maize genome poses several significant challenges to the application of association mapping, the ongoing genome sequencing project will ultimately allow for a thorough genome-wide examination of nucleotide polymorphism-trait association.
引用
收藏
页码：155 / 160
页数：6
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