Dual-channel fiber-probe for simultaneous imaging of swept source optical coherence tomography and fluorescence spectroscopy

被引：2

作者：

Min, Eun Jung ^{[1
]}

Lee, Jae Hwi ^{[1
]}

Shin, Jun Geun ^{[1
]}

Kwon, Seong-Min

You, Hyun

Yoon, Jung-Hoon

Kim, Yong-Chul

Lee, Byeong Ha ^{[1
]}

机构：

[1] Gwangju Inst Sci & Technol, Sch Informat & Commun, Kwangju 500712, South Korea

来源：

OPTICAL FIBERS AND SENSORS FOR MEDICAL DIAGNOSTICS AND TREATMENT APPLICATIONS XIII | 2013年 / 8576卷

关键词：

SS OCT-FS system; dual-channel fiber scanning probe; ENDOSCOPE; TISSUES; OCT;

D O I：

10.1117/12.2003749

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

We propose a dual-channel fiber scanning probe for simultaneous measurement of swept source optical coherence tomography (SS OCT) and fluorescence spectroscopy (FS) signals. For the purpose, SS OCT and FS system were combined by adopting the specially fabricated double cladding fiber (DCF) and wavelength division multiplexer (WDM) coupler, and DCF fiber was directly connected to sample arm of DCF coupler for fiber-based probe. Moreover, for sample scanning, the fiber was driven by piezoelectric bender. Since DCF has dual-channel configuration consists of core and inner cladding, both OCT and FS signals propagate through the two channels at the same time. Therefore, the suggested system enables multifunctional imaging that would make it possible to determine a more specific diagnosis. To demonstrate the feasibility of the probe, a photosensitizer injected in-vivo mice were imaged with scanning speed of 16 Hz and scanning range of 2 mm.

引用

页数：7

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