GalX regulates the D-galactose oxido-reductive pathway in Aspergillus niger

被引：30

作者：

Gruben, Birgit S. ^{[1
,2
]}

Zhou, Miaomiao ^{[1
]}

de Vries, Ronald P. ^{[1
,2
]}

机构：

[1] CBS KNAW Fungal Biodivers Ctr, NL-3584 CT Utrecht, Netherlands

[2] Univ Utrecht, Microbiol & Kluyver Ctr Genom Ind Fermentat, Utrecht, Netherlands

来源：

FEBS LETTERS | 2012年 / 586卷 / 22期

关键词：

Galactose catabolism; Regulation; Oxido-reductive pathway; Leloir pathway; Aspergillus niger; D-XYLOSE REDUCTASE; ALPHA-GALACTOSIDASE; BETA-GALACTOSIDASE; SACCHAROMYCES-CEREVISIAE; CELLULASE INDUCTION; FILAMENTOUS FUNGI; HYPOCREA-JECORINA; GENE; DEGRADATION; NIDULANS;

D O I：

10.1016/j.febslet.2012.09.029

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Galactose catabolism in Aspergillus nidulans is regulated by at least two regulators, GalR and GalX. In Aspergillus niger only GalX is present, and its role in D-galactose catabolism in this fungus was investigated. Phenotypic and gene expression analysis of a wild type and a galX disruptant revealed that GalX regulates the D-galactose oxido-reductive pathway, but not the Leloir pathway in A. niger. (c) 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

引用

页码：3980 / 3985

页数：6

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