We present a new route for converting glucose into a bioadvantaged monomer through a hybrid process combining biological and chemical conversions. This monomer gives access to a new family of unsaturated polyamides (bioadvantaged nylon 6,6) with superior performance compared to their petrochemical counterparts. Specifically, we demonstrate that this chemical enables the introduction of new functionalities, hereby facilitating the synthesis of nylon 6,6 with tailored functional properties.