共 2 条
Differences of milk-transmitted murine mammary tumor virus (MMTV) among mouse strains
被引:0
作者:
Sayama, K
Takeda, Y
Hashimoto, H
Kaneko, T
Matsuzawa, A
机构:
[1] Shizuoka Univ, Dept Anim Sci, Fac Agr, Shizuoka 422, Japan
[2] Univ Tokyo, Inst Med Sci, Lab Anim Res Ctr, Minato Ku, Tokyo 108, Japan
[3] Meijigakuin Univ, Lab Gen Biol, Totsuka Ku, Yokohama, Kanagawa 244, Japan
来源:
IN VIVO
|
1999年
/
13卷
/
02期
关键词:
murine mammary tumor virus;
mouse strains;
pregnancy-dependent tumor;
superantigen specificity;
D O I:
暂无
中图分类号:
R-3 [医学研究方法];
R3 [基础医学];
学科分类号:
1001 ;
摘要:
To clarify the oncological differences of milk-transmitted Murine Mammary Tumor Virus (MMTV) in various strains, BALB/c mice were foster-nursed on C3H/He, GR, DDD, DDD/1-Mtv-2/Mtv-2 and FM strains and observed Sol the development and morphology of mammary tumors, followed by testing tumors for pregnancy dependence (PD) after transplantation. MMTV were different in tumorigenicity and morphology and PD of induced tumors among the mouse strains. These differences of MMTV appeal-ed not to be parallel with the difference in specificity; of superantigens which nle encoded by MMTV on the previous report. Interestingly, host factors influenced the properties of MMTV produced by the same endogenous Mtv gene.
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页码:135 / 139
页数:5
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