Challenges in Interpreting Multivariable Mendelian Randomization: Might "Good Cholesterol" Be Good After All?

被引:13
作者
Holmes, Michael V. [1 ,2 ,3 ,4 ,5 ]
Smith, George Davey [5 ,6 ]
机构
[1] Univ Oxford, Med Res Council, Populat Hlth Res Unit, Oxford, England
[2] Univ Oxford, Nuffield Dept Populat Hlth, Clin Trial Serv Unit, Oxford, England
[3] Univ Oxford, Nuffield Dept Populat Hlth, Epidemiol Studies Unit, Oxford, England
[4] Oxford Univ Hosp, Oxford Biomed Res Ctr, Natl Inst Hlth Res, Oxford, England
[5] Univ Bristol, Med Res Council, Integrat Epidemiol Unit, Oakfield House, Bristol BS8 2BN, Avon, England
[6] Univ Bristol, Populat Hlth Sci, Bristol, Avon, England
基金
英国医学研究理事会;
关键词
CORONARY-HEART-DISEASE; LDL CHOLESTEROL; GENETIC-VARIANTS; RISK-FACTORS; ASSOCIATION; PATHWAYS; LIPIDS; AGE; TRIGLYCERIDES; METAANALYSIS;
D O I
10.1053/j.ajkd.2017.10.006
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:149 / 153
页数:5
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