How reliable are Hounsfield-unit measurements in forensic radiology?

被引:34
作者
Ruder, Thomas D. [1 ]
Thali, Yannick [1 ]
Schindera, Sebastian T. [2 ]
Dalla Torre, Simon A. [3 ]
Zech, Wolf-Dieter [4 ]
Thali, Michael J. [1 ,4 ]
Ross, Steffen [1 ]
Hatch, Gary M. [1 ]
机构
[1] Univ Bern, Inst Forens Med, Ctr Forens Imaging & Virtopsy, CH-3012 Bern, Switzerland
[2] Univ Hosp Bern, Inselspital, Inst Radiol, CH-3010 Bern, Switzerland
[3] Swiss Agcy Therapeut Prod, Swissmed, CH-3000 Bern 9, Switzerland
[4] Univ Bern, Inst Forens Med, Dept Forens Pathol, CH-3012 Bern, Switzerland
关键词
Forensic radiology; Computed tomography; HU measurements; Object identification; Reliability; Reference model; MULTISLICE COMPUTED-TOMOGRAPHY; BONE-MINERAL MEASUREMENTS; QUALITY-CONTROL; PHANTOM; CT; STANDARDIZATION; IDENTIFICATION; SPINE; QCT; DXA;
D O I
10.1016/j.forsciint.2012.03.004
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
Objective: To assess the reliability of computed tomography (CT) numbers, also known as Hounsfield-units (HU) in the differentiation and identification of forensically relevant materials and to provide instructions to improve the reproducibility of HU measurements in daily forensic practice. Materials and methods: We scanned a phantom containing non-organic materials (glass, rocks and metals) on three different CT scanners with standardized parameters. The t-test was used to assess the influence of the scanner, the size and shape of different types of regions-of-interest (ROI), the composition and shape of the object, and the reader performance on HU measurements. Intra-class correlation coefficient was used to assess intra- and inter-reader reliability. Results: HU values did not change significantly as a function of ROI-shape or -size (p > 0.05). Intra-reader reliability reached ICC values >0.929 (p < 0.001). Inter-reader reliability was also excellent with an ICC of 0.994 (p < 0.001). Four of seven objects yielded significantly different CT numbers at different levels within the object (p < 0.05). In 6/7 objects the HU changed significantly from CT scanner to CT scanner (p < 0.05). Conclusion: Reproducible CT number measurements can be achieved through correct ROI-placement and repeat measurements within the object of interest. However, HU may differ from CT-scanner to CT-scanner. In order to obtain comparable CT numbers we suggest that a dedicated Forensic Reference Phantom be developed. (c) 2012 Elsevier Ireland Ltd. All rights reserved.
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页码:219 / 223
页数:5
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