The first case of systemic lupus erythematosus (SLE) triggered by COVID-19 infection

被引：84

作者：

Bonometti, R. ^{[1
]}

Sacchi, M. C. ^{[2
]}

Stobbione, P. ^{[3
]}

Lauritano, E. C. ^{[1
]}

Tamiazzo, S. ^{[2
]}

Marchegiani, A. ^{[4
]}

Novara, E. ^{[5
]}

Molinaro, E. ^{[5
]}

Benedetti, I ^{[6
]}

Massone, L. ^{[4
]}

Bellora, A. ^{[4
]}

Boverio, R. ^{[1
]}

机构：

[1] Santi Antonio & Biagio & Cesare Arrigo Hosp, Dept Emergency Med, Alessandria, Italy

[2] Santi Antonio & Biagio & Cesare Arrigo Hosp, Autoimmunol & Anal Lab Unit, Alessandria, Italy

[3] Santi Antonio & Biagio & Cesare Arrigo Hosp, Dept Rheumatol, Alessandria, Italy

[4] Santi Antonio & Biagio & Cesare Arrigo Hosp, Geriatr Div, Alessandria, Italy

[5] Univ Pavia, Dept Emergency Med, IRCCS San Matteo Hosp Fdn, Pavia, Italy

[6] Univ Pavia, Dept Internal Med, IRCCS San Matteo Hosp Fdn, Pavia, Italy

来源：

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES | 2020年 / 24卷 / 18期

关键词：

COVID-19; Autornmunity; ESL; Lupus;

D O I：

10.26355/eurrev_202009_23060

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Coronavirus disease 2019 (COVID-19) is a respiratory tract infection caused by a newly emergent coronavirus, SARS-CoV-2. The acute phase may be followed by a second phase actually not yet completely understood but probably associated to an autoimmune activation. At the moment is not possible to clearly define an association between immunological findings and pathological symptoms, however, this case report describes the case of a patient who following COVID-19 infection development autoimmune antibodies who persist in time longer than viral phase. Those antibodies can be responsible for the multi pathological clinical picture showed from our patient that, according to EULAR 2019 criteria, could be classified as systemic lupus erythematosus (SLE). SLE is probably one of the possible chronic rheumatologic diseases triggers by COVID-19 and this is the first case of SLE with vasculitis actually described in literature.

引用

页码：9695 / 9697

页数：3

共 7 条

[1] 2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus [J].

Aringer, Martin ;

Costenbader, Karen ;

Daikh, David ;

Brinks, Ralph ;

Mosca, Marta ;

Ramsey-Goldman, Rosalind ;

Smolen, Josef S. ;

Wofsy, David ;

Boumpas, Dimitrios T. ;

Kamen, Diane L. ;

Jayne, David ;

Cervera, Ricard ;

Costedoat-Chalumeau, Nathalie ;

Diamond, Betty ;

Gladman, Dafna D. ;

Hahn, Bevra ;

Hiepe, Falk ;

Jacobsen, Soren ;

Khanna, Dinesh ;

Lerstrom, Kirsten ;

Massarotti, Elena ;

McCune, Joseph ;

Ruiz-Irastorza, Guillermo ;

Sanchez-Guerrero, Jorge ;

Schneider, Matthias ;

Urowitz, Murray ;

Bertsias, George ;

Hoyer, Bimba F. ;

Leuchten, Nicolai ;

Tani, Chiara ;

Tedeschi, Sara K. ;

Touma, Zahi ;

Schmajuk, Gabriela ;

Anic, Branimir ;

Assan, Florence ;

Chan, Tak Mao ;

Clarke, Ann Elaine ;

Crow, Mary K. ;

Czirjak, Laszlo ;

Doria, Andrea ;

Graninger, Winfried ;

Halda-Kiss, Bernadett ;

Hasni, Sarfaraz ;

Izmirly, Peter M. ;

Jung, Michelle ;

Kumanovics, Gabor ;

Mariette, Xavier ;

Padjen, Ivan ;

Pego-Reigosa, Jose M. ;

Romero-Diaz, Juanita .

ANNALS OF THE RHEUMATIC DISEASES, 2019, 78 (09) :1151-1159

[2] Vasculitis in systemic lupus erythematosus [J].

Drenkard, C ;

Villa, AR ;

Reyes, E ;

Abello, M ;

AlarconSegovia, D .

LUPUS, 1997, 6 (03) :235-242

[3] Systemic lupus erythematosus: Diagnosis and clinical management [J].

Fava, Andrea ;

Petri, Michelle .

JOURNAL OF AUTOIMMUNITY, 2019, 96 :1-13

[4]

Feng ZJ, 2020, CHINA CDC WEEKLY, V0002

[5] Clinical course of coronavirus disease 2019 (COVID-19) in a series of 17 patients with systemic lupus erythematosus under long-term treatment with hydroxychloroquine [J].

Mathian, Alexis ;

Mahevas, Matthieu ;

Rohmer, Julien ;

Roumier, Mathilde ;

Cohen-Aubart, Fleur ;

Amador-Borrero, Blanca ;

Barrelet, Audrey ;

Chauvet, Cecile ;

Chazal, Thibaud ;

Delahousse, Michel ;

Devaux, Mathilde ;

Euvrard, Romain ;

Fadlallah, Jehane ;

Florens, Nans ;

Haroche, Julien ;

Hie, Miguel ;

Juillard, Laurent ;

Lhote, Raphael ;

Maillet, Thibault ;

Richard-Colmant, Gaelle ;

Palluy, Jean Baptiste ;

Pha, Micheline ;

Perard, Laurent ;

Remy, Philippe ;

Riviere, Etienne ;

Sene, Damien ;

Seve, Pascal ;

Morelot-Panzini, Capucine ;

Viallard, Jean-Francois ;

Virot, Jean-Simon ;

Benameur, Neila ;

Zahr, Noel ;

Yssel, Hans ;

Godeau, Bertrand ;

Amoura, Zahir .

ANNALS OF THE RHEUMATIC DISEASES, 2020, 79 (06) :837-+

[6] Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study [J].

Yang, Xiaobo ;

Yu, Yuan ;

Xu, Jiqian ;

Shu, Huaqing ;

Xia, Jia'an ;

Liu, Hong ;

Wu, Yongran ;

Zhang, Lu ;

Yu, Zhui ;

Fang, Minghao ;

Yu, Ting ;

Wang, Yaxin ;

Pan, Shangwen ;

Zou, Xiaojing ;

Yuan, Shiying ;

Shang, You .

LANCET RESPIRATORY MEDICINE, 2020, 8 (05) :475-481

[7]

ZHOU Y, 2020, CLIN TRANSL SCI, DOI [10.1111/cts.12805, DOI 10.1111/CTS.12805.D0I:10.1111/CTS.12805]

← 1 →