Shuttle-Based Fluorogenic Silver-Cluster Biolabels

被引：277

作者：

Yu, Junhua

Choi, Sungmoon

Dickson, Robert M. ^{[1
]}

机构：

[1] Georgia Inst Technol, Sch Chem & Biochem, Atlanta, GA 30332 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 02期

关键词：

DNA; fluorescent probes; imaging agents; nanostructures; silver; QUANTUM DOTS; HIGHLY FLUORESCENT; AG NANOCLUSTERS; FLUOROPHORES; PROTEIN; CELLS;

D O I：

10.1002/anie.200804137

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Clustering together: A shuttle-based fluorogenic cluster transfer, in which silver clusters (SCs) are directly transferred from a low-molecular-weight poly(acrylic acid) (PA) shuttle to a single-stranded DNA (ssDNA) tag on the protein of interest (see picture), proceeds with excellent specificity. Upon transfer, the cluster fluorescence increases more than ten times, which provides bright, photostable labeling. (Figure Presented). © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：318 / 320

页数：3

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