FDA/NIH/WHO public workshop on immune correlates of protection against influenza A viruses in support of pandemic vaccine development, Bethesda, Maryland, US, December 10-11, 2007

被引：80

作者：

Eichelberger, Maryna ^{[1
]}

Golding, Hana ^{[1
]}

Hess, Maureen ^{[1
]}

Weir, Jerry ^{[1
]}

Subbarao, Kanta ^{[2
]}

Luke, Catherine J. ^{[2
]}

Friede, Martin ^{[3
]}

Wood, David ^{[3
]}

机构：

[1] US FDA, Ctr Biol Evaluat & Res, Off Vaccines Res & Review, Div Viral Prod, Bethesda, MD 20892 USA

[2] NIAID, Infect Dis Lab, NIH, Bethesda, MD 20892 USA

[3] WHO, CH-1211 Geneva, Switzerland

来源：

VACCINE | 2008年 / 26卷 / 34期

关键词：

influenza type A; avian influenza; pandemic; correlated of protection;

D O I：

10.1016/j.vaccine.2008.06.012

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The goals of the workshop were to identify gaps in our knowledge and abilities to address the unique challenges encountered in the development of vaccines intended to protect against pandemic influenza and to facilitate implementation of a global research agenda to improve efficacy assessment of pandemic influenza vaccines. This workshop included discussions on: (i) current knowledge regarding immune correlates of protection against seasonal influenza; (ii) human immune responses to avian influenza infection and vaccines for novel influenza viruses: (iii) limitations of currently available assays to evaluate vaccine immunogenicity; and (iv) potential insights from animal models for correlates of protection against avian influenza.

引用

页码：4299 / 4303

页数：5

共 5 条

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Katz, JM
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[4] Safety and immunogenicity of an inactivated subvirion influenza A (H5N1) vaccine
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[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2006, 354 (13) : 1343 - 1351
[5] *WHO, WHO TECHNIC IN PRESS

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