Settlement control is the keystone of high-speed railway foundation. This paper is based on the long-term site observation to settlement of typical sections on the overall structure of piled raft in actual application at Xiuzhou Section in Jing-Hu High-speed Railway. The paper analyzes the land settlement, layered settlement, lateral displacement, excessive pore pressure, horizontal displacement and other deformation and characteristics of foundation of piled raft structure. In addition, the deformation characteristics of the natural foundation and piled raft foundation are compared to understand the working performance and application effects of piled raft structure ([1]). The results show that the piled raft changes the deformation features of natural foundation, so that the foundation settlement mainly occurs in the subjacent bed, and the total settling amount reduces greatly. Piled raft can greatly reduce the lateral deformation of foundation soil and additional settlement resulting from it. The piled raft structure improves not only the deformation modulus and synthetic stiffness of the reinforced area, but also the capability of anti-deformation under external load, as a result, its effect of controlling roadbed settlement is obvious.