CHRONIC KIDNEY DISEASE Phosphate binder therapy-cracks in the tower of strength?

被引：2

作者：

Evenepoel, Pieter ^{[1
]}

Meijers, Bjorn ^{[1
]}

机构：

[1] Univ Hosp Gasthuisberg, Div Nephrol, Dept Microbiol & Immunol, B-3000 Louvain, Belgium

来源：

NATURE REVIEWS NEPHROLOGY | 2012年 / 8卷 / 11期

关键词：

ARTERY CALCIFICATION; SEVELAMER;

D O I：

10.1038/nrneph.2012.219

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Oral phosphate binder therapy is considered a 'tower of strength' in the ever-expanding armamentarium of drugs used to treat abnormal mineral metabolism in patients with chronic kidney disease (CKD) and use of these agents early in the course of CKD is gaining much interest. Recent data from a randomized controlled study by Block et al. challenge this strategy, raise doubts about its safety and indicate the need for additional studies of hard end points.

引用

页码：615 / 616

页数：2

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