O-GlcNAc Modification Prevents Peptide-Dependent Acceleration of α-Synuclein Aggregation

被引：52

作者：

Marotta, Nicholas P. ^{[1
,2
]}

Cherwien, Carli A. ^{[1
,2
]}

Abeywardana, Tharindumala ^{[1
,2
]}

Pratt, Matthew R. ^{[1
,2
]}

机构：

[1] Univ So Calif, Dept Chem, Los Angeles, CA 90089 USA

[2] Univ So Calif, Dept Mol & Computat Biol, Los Angeles, CA 90089 USA

来源：

CHEMBIOCHEM | 2012年 / 13卷 / 18期

关键词：

aggregation; glycosylation; O-GlcNAc; Parkinson's disease; synuclein; PARKINSONS-DISEASE; POSTTRANSLATIONAL MODIFICATIONS; N-ACETYLGLUCOSAMINE; LEWY BODIES; HUMAN BRAIN; GENE; PHOSPHORYLATION; FIBRILLATION; MUTATION; UBIQUITINATION;

D O I：

10.1002/cbic.201200478

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：2665 / 2670

页数：6

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