Efficient and Convenient Palladium-Catalyzed Amination of Allylic Alcohols with N-Heterocycles

被引：54

作者：

Banerjee, Debasis ^{[1
]}

Jagadeesh, Rajenahally V. ^{[1
]}

Junge, Kathrin ^{[1
]}

Junge, Henrik ^{[1
]}

Beller, Matthias ^{[1
]}

机构：

[1] Univ Rostock, Leibniz Inst Katalyse, D-18059 Rostock, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2012年 / 51卷 / 46期

关键词：

allylic substitution; amination; nitrogen heterocycles; palladium; sustainable chemistry; DIRECT SUBSTITUTION; BORROWING HYDROGEN; PROPARGYLIC ALCOHOLS; PRIMARY AMINES; ALLYLATION; ACTIVATION; LIGANDS; ANALOGS; SULFONAMIDES; COMPLEXES;

D O I：

10.1002/anie.201206319

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Atom economic: A commercially available palladium catalyst system is applied for an environmentally benign allylation of electron-deficient N-heterocycles using allylic alcohols (see scheme). The system is also applied for the N-allylation of biologically important uridine and thymidine derivatives. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：11556 / 11560

页数：5

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