Mechanism of myosin phosphatase inhibition via phosphorylation of MYPT1 subunit by RhoA/ROCK

被引：0
|
作者：
Eto, Masumi [1 ]
Choudhury, Nandini [2 ]
Stevenson, Andra [2 ]
Somlyo, Avril V. [2 ]
机构：
[1] Thomas Jefferson Univ, Philadelphia, PA 19107 USA
[2] Univ Virginia, Charlottesville, VA USA
来源：
FASEB JOURNAL | 2008年 / 22卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Urocortin decreases via cAMP the phosphorylation of MYPT1 and increases the myosin phosphatase activity
    Lubomirov, L. T.
    Schubert, R.
    Gagov, H.
    Dwidanova, D.
    Pfitzer, G.
    BIOFIZIKA, 2006, 51 (05): : 773 - 780
  • [2] Interaction of Myosin Phosphatase Target Subunit (MYPT1) with Myosin Phosphatase-RhoA Interacting Protein (MRIP): A Role of Glutamic Acids in the Interaction
    Lee, Eunhee
    Stafford, Walter F., III
    PLOS ONE, 2015, 10 (10):
  • [3] The involvement of phosphorylation of myosin phosphatase targeting subunit 1 (MYPT1) and MYPT1 isoform expression in NO/cGMP mediated differential vasoregulation of cerebral arteries compared to systemic arteries
    Lubomirov, L. T.
    Papadopoulos, S.
    Filipova, D.
    Baransi, S.
    Todorovic, D.
    Lake, P.
    Metzler, D.
    Hilsdorf, S.
    Schubert, R.
    Schroeter, M. M.
    Pfitzer, G.
    ACTA PHYSIOLOGICA, 2018, 224 (01)
  • [4] Chk2-dependent phosphorylation of myosin phosphatase targeting subunit 1 (MYPT1) regulates centrosome maturation
    Nai, Shanshan
    Shi, Yingxin
    Ru, Huanwei
    Ding, Yuehe
    Geng, Qizhi
    Li, Zhe
    Dong, Meng-Qiu
    Xu, Xingzhi
    Li, Jing
    CELL CYCLE, 2019, 18 (20) : 2651 - 2659
  • [5] ERK Controls Myosin Phosphatase and Cell Migration through RSK Phosphorylation of MYPT1
    Mendoza, Michelle C.
    Samson, Shiela
    Elliott, Andrew
    Carney, Keith
    FASEB JOURNAL, 2019, 33
  • [6] Phasic contractions of isolated human myometrium are associated with Rho-kinase (ROCK)-dependent phosphorylation of myosin phosphatase-targeting subunit (MYPT1)
    Hudson, Claire A.
    Heesom, Kate J.
    Bernal, Andres Lopez
    MOLECULAR HUMAN REPRODUCTION, 2012, 18 (05) : 265 - 279
  • [7] Spinocerebellar ataxia type 10 protein, binds to Myosin phosphatase target subunit 1 (MYPT1)
    Nagamitsu, S
    Zhang, R
    Matsuura, T
    Epstein, HF
    Ashizawa, T
    AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 71 (04) : 319 - 319
  • [8] Reconstituted Human Myosin Light Chain Phosphatase Reveals Distinct Roles of Two Inhibitory Phosphorylation Sites of the Regulatory Subunit, MYPT1
    Khasnis, Mukta
    Nakatomi, Akiko
    Gumpper, Kristyn
    Eto, Masumi
    BIOCHEMISTRY, 2014, 53 (16) : 2701 - 2709
  • [9] Smooth Muscle-Specific Myosin Phosphatase Target Subunit 1 (MYPT1): An Important Piece of the Puzzle
    Rattan, Satish
    GASTROENTEROLOGY, 2013, 145 (06) : 1494 - 1495
  • [10] Overexpression of Myosin Phosphatase Target Subunit 1 (MYPT1) Inhibits Tumor Progression and Metastasis of Gastric Cancer
    Wang, Fengyong
    Sun, Yuanshui
    MEDICAL SCIENCE MONITOR, 2018, 24 : 2508 - 2517
12345