Estimation of multi-walled carbon nanotubes toxicity in vitro

被引:35
作者
Prylutska, S. V. [2 ]
Grynyuk, I. I. [2 ]
Matyshevska, O. P. [2 ]
Yashchuk, V. M. [3 ]
Prylutskyy, Yu. I. [1 ]
Ritter, U. [4 ]
Scharff, P. [4 ]
机构
[1] Kyiv Natl Shevchenko Univ, Dept Biophys, UA-01033 Kiev, Ukraine
[2] Kyiv Natl Shevchenko Univ, Dept Biochem, UA-01033 Kiev, Ukraine
[3] Kyiv Natl Shevchenko Univ, Dept Phys, UA-01033 Kiev, Ukraine
[4] Tech Univ Ilmenau, Inst Phys, D-98684 Ilmenau, Germany
关键词
multi-walled carbon nanotubes; optical absorption spectra; cytotoxicity;
D O I
10.1016/j.physe.2007.07.017
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
It was shown that the multi-walled carbon nanotubes at concentrations up to 25 mu g/ml do not show toxic effects on rat erythrocytes and thymocytes in cell suspension, while at concentration 50 mu g/ml caused the acceleration of erythrocyte hemolysis, decrease of the number of viable thymocytes in suspension and inhibition of mitochondrial electron-transporting chain. (C) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:2565 / 2569
页数:5
相关论文
共 9 条
  • [1] CARMICHAEL J, 1987, CANCER RES, V47, P936
  • [2] NONCOLORIMETRIC MEASUREMENT OF CELL-ACTIVITY IN 3-DIMENSIONAL HISTOCULTURE USING THE TETRAZOLIUM DYE 3-(4,5-DIMETHYLTHIAZOL-2-YL)-2,5-DIPHENYLTETRAZOLIUM BROMIDE - THE PIXEL IMAGE-ANALYSIS OF FORMAZAN CRYSTALS
    COLANGELO, D
    GUO, HY
    CONNORS, KM
    SILVESTRO, L
    HOFFMAN, RM
    [J]. ANALYTICAL BIOCHEMISTRY, 1992, 205 (01) : 8 - 13
  • [3] Dresselhaus MS, 1996, Science of fullerenes and carbon nanotubes: Their properties and applications
  • [4] Functionalized carbon nanotubes are non-cytotoxic and preserve the functionality of primary immune cells
    Dumortier, Helene
    Lacotte, Stephanie
    Pastorin, Giorgia
    Marega, Riccardo
    Wu, Wei
    Bonifazi, Davide
    Briand, Jean-Paul
    Prato, Maurizio
    Muller, Sylviane
    Bianco, Alberto
    [J]. NANO LETTERS, 2006, 6 (07) : 1522 - 1528
  • [5] Harris P.J.F., 1999, Carbon Nanotubes and Related Structures, DOI DOI 10.1017/CBO9780511605819
  • [6] HIMMERLICH M, 2007, CHARACTERISATION MUL
  • [7] Carbon nanotubes as intracellular protein transporters: Generality and biological functionality
    Kam, NWS
    Dai, HJ
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (16) : 6021 - 6026
  • [8] Multi-walled carbon nanotube interactions with human epidermal keratinocytes
    Monteiro-Riviere, NA
    Nemanich, RJ
    Inman, AO
    Wang, YYY
    Riviere, JE
    [J]. TOXICOLOGY LETTERS, 2005, 155 (03) : 377 - 384
  • [9] Respiratory toxicity of multi-wall carbon nanotubes
    Muller, J
    Huaux, F
    Moreau, N
    Misson, P
    Heilier, JF
    Delos, M
    Arras, M
    Fonseca, A
    Nagy, JB
    Lison, D
    [J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 2005, 207 (03) : 221 - 231