Estimation of multi-walled carbon nanotubes toxicity in vitro

被引：35

作者：

Prylutska, S. V. ^{[2
]}

Grynyuk, I. I. ^{[2
]}

Matyshevska, O. P. ^{[2
]}

Yashchuk, V. M. ^{[3
]}

Prylutskyy, Yu. I. ^{[1
]}

Ritter, U. ^{[4
]}

Scharff, P. ^{[4
]}

机构：

[1] Kyiv Natl Shevchenko Univ, Dept Biophys, UA-01033 Kiev, Ukraine

[2] Kyiv Natl Shevchenko Univ, Dept Biochem, UA-01033 Kiev, Ukraine

[3] Kyiv Natl Shevchenko Univ, Dept Phys, UA-01033 Kiev, Ukraine

[4] Tech Univ Ilmenau, Inst Phys, D-98684 Ilmenau, Germany

来源：

PHYSICA E-LOW-DIMENSIONAL SYSTEMS & NANOSTRUCTURES | 2008年 / 40卷 / 07期

关键词：

multi-walled carbon nanotubes; optical absorption spectra; cytotoxicity;

D O I：

10.1016/j.physe.2007.07.017

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

It was shown that the multi-walled carbon nanotubes at concentrations up to 25 mu g/ml do not show toxic effects on rat erythrocytes and thymocytes in cell suspension, while at concentration 50 mu g/ml caused the acceleration of erythrocyte hemolysis, decrease of the number of viable thymocytes in suspension and inhibition of mitochondrial electron-transporting chain. (C) 2007 Elsevier B.V. All rights reserved.

引用

页码：2565 / 2569

页数：5

共 9 条

[1]

CARMICHAEL J, 1987, CANCER RES, V47, P936

[2] NONCOLORIMETRIC MEASUREMENT OF CELL-ACTIVITY IN 3-DIMENSIONAL HISTOCULTURE USING THE TETRAZOLIUM DYE 3-(4,5-DIMETHYLTHIAZOL-2-YL)-2,5-DIPHENYLTETRAZOLIUM BROMIDE - THE PIXEL IMAGE-ANALYSIS OF FORMAZAN CRYSTALS [J].

COLANGELO, D ;

GUO, HY ;

CONNORS, KM ;

SILVESTRO, L ;

HOFFMAN, RM .

ANALYTICAL BIOCHEMISTRY, 1992, 205 (01) :8-13

[3]

Dresselhaus MS, 1996, Science of fullerenes and carbon nanotubes: Their properties and applications

[4] Functionalized carbon nanotubes are non-cytotoxic and preserve the functionality of primary immune cells [J].

Dumortier, Helene ;

Lacotte, Stephanie ;

Pastorin, Giorgia ;

Marega, Riccardo ;

Wu, Wei ;

Bonifazi, Davide ;

Briand, Jean-Paul ;

Prato, Maurizio ;

Muller, Sylviane ;

Bianco, Alberto .

NANO LETTERS, 2006, 6 (07) :1522-1528

[5]

Harris P.J.F., 1999, Carbon Nanotubes and Related Structures, DOI DOI 10.1017/CBO9780511605819

[6]

HIMMERLICH M, 2007, CHARACTERISATION MUL

[7] Carbon nanotubes as intracellular protein transporters: Generality and biological functionality [J].

Kam, NWS ;

Dai, HJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (16) :6021-6026

[8] Multi-walled carbon nanotube interactions with human epidermal keratinocytes [J].

Monteiro-Riviere, NA ;

Nemanich, RJ ;

Inman, AO ;

Wang, YYY ;

Riviere, JE .

TOXICOLOGY LETTERS, 2005, 155 (03) :377-384

[9] Respiratory toxicity of multi-wall carbon nanotubes [J].

Muller, J ;

Huaux, F ;

Moreau, N ;

Misson, P ;

Heilier, JF ;

Delos, M ;

Arras, M ;

Fonseca, A ;

Nagy, JB ;

Lison, D .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 2005, 207 (03) :221-231

← 1 →