Perceived and actual obesity in childhood and adolescence and risk of adult depression

被引:22
作者
Sanchez-Villegas, Almudena [1 ,2 ]
Field, Alison E. [3 ,4 ]
O'Reilly, Eilis J. [5 ,6 ]
Fava, Maurizio [7 ]
Gortmaker, Steven [8 ]
Kawachi, Ichiro [4 ,8 ]
Ascherio, Alberto [5 ,6 ]
机构
[1] Univ Las Palmas Gran Canaria, Dept Clin Sci, Las Palmas Gran Canaria 35008, Spain
[2] Univ Navarra, Dept Prevent Med & Publ Hlth, E-31080 Pamplona, Spain
[3] Childrens Hosp Boston, Dept Med, Div Adolescent Young Adult Med, Boston, MA USA
[4] Brigham & Womens Hosp, Dept Med, Channing Lab, Boston, MA USA
[5] Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA
[6] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
[7] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Psychiat Depress Clin & Res Program, Boston, MA USA
[8] Harvard Univ, Sch Publ Hlth, Dept Soc Human Dev & Hlth, Boston, MA 02115 USA
关键词
C-REACTIVE PROTEIN; BODY-MASS INDEX; SELF-ESTEEM; BIRTH COHORT; SOCIOECONOMIC POSITION; CARDIOVASCULAR-DISEASE; OVERWEIGHT CHILDREN; MAJOR DEPRESSION; YOUNG ADULTHOOD; SWEDISH MEN;
D O I
10.1136/jech-2012-201435
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Background Obesity in childhood and adolescence has important health consequences, but its relation to risk of adult depression remains uncertain. Objective To examine the effect of perceived and actual obesity during childhood and adolescence on prevalence and incidence of adult depression risk. Methods Cohort study of 91 798 female registered nurses followed longitudinally for 12 years. Results As compared with lean women of the same age, women in the two highest categories of body shape at age 10 had both higher prevalence (OR = 2.59, 95% CI 1.46 to 4.61) and incidence (OR = 2.01, 95% CI 1.08 to 3.71) of depression. Similar results were obtained for body shape at age 20 (OR = 3.43 for prevalence and OR = 2.03 for incidence) and for body mass index (BMI) at age 18 (OR = 2.92 for BMI >= 40 kg/m(2)). These associations remained significant after adjustment for multiple confounders. Conclusion These results indicate that childhoodeadolescence obesity is a strong and independent risk factor for adult depression.
引用
收藏
页码:81 / 86
页数:6
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