A simple two-step sequence for the synthesis of novel 4-aryl-4,5-dihydro-6H-[1,3]dioxolo[4,5-h]pyrrolo[1,2-a][1]benzazepin-6-ones from 6-amino-3,4-methylenedioxyacetophenone

被引：12
作者：
Abonia, Rodrigo [1 ]
Cuervo, Paola [1 ]
Insuasty, Braulio [1 ]
Quiroga, Jairo [1 ]
Nogueras, Manuel [2 ]
Cobo, Justo [2 ]
机构：
[1] Univ Valle, Dept Quim, Cali 25360, Colombia
[2] Univ Jaen, Dept Quim Inorgan & Organ, Jaen 23071, Spain
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2008年 / 2008卷 / 27期
关键词：
phosphoric acid; Michael addition; chalcones; cyclization; heterocycles;
D O I：
10.1002/ejoc.200800493
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Herein is provided an efficient and two-step short procedure for the synthesis of novel 6H-[1,3]dioxolobenzo[4,5-h]pyrrolo[1,2-a][1]benezazepin-6-one derivatives promoted by commercial phosphoric acid. In a parallel approach some pyrrolyl chalcones were isolated that proved to behave as intermediates for the title compounds. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008).
引用
收藏
页码：4684 / 4689
页数：6
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