Target DNA induced switches of DNA polymerase activity

被引：33

作者：

Park, Ki Soo ^{[1
]}

Lee, Chang Yeol ^{[1
]}

Park, Hyun Gyu ^{[1
]}

机构：

[1] Korea Adv Inst Sci & Technol, Dept Chem & Biomol Engn, Program BK21, Taejon 305701, South Korea

来源：

CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 49期

基金：

新加坡国家研究基金会;

关键词：

APTAMERIC ENZYME SUBUNIT; GRAPHENE OXIDE; FLUORESCENCE DETECTION; MOLECULAR BEACONS; PROBES; HYBRIDIZATION; PCR; POLYMERIZATION; PLATFORM; BINDING;

D O I：

10.1039/c5cc02060c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel concept that target DNA can induce switching of DNA polymerase activity is devised. The method relies on the finding that a DNA aptamer can undergo conformational change upon hybridization with a complementary target DNA, which leads to activation or inactivation of DNA polymerase. This strategy is utilized to identify the presence of target DNA with high levels of sensitivity and selectivity.

引用

页码：9942 / 9945

页数：4

共 50 条

[41] Nick Induced Dynamics in Supercoiled DNA Facilitates the Protein Target Search Process
Sangeeta, Arnab
Bhattacherjee, Arnab
JOURNAL OF PHYSICAL CHEMISTRY B, 2024, 128 (34): : 8246 - 8258
[42] A dual-mode strategy based on β-galactosidase and target-induced DNA polymerase protection for transcription factor detection using colorimetry and a glucose meter
Qian, Xinmei
Zhang, Heng
Zheng, Mingyu
Li, Chunxiang
Wang, Jinglun
Huang, Haowen
Deng, Keqin
ANALYST, 2023, 148 (23) : 6078 - 6086
[43] DNA polymerase delta governs parental histone transfer to DNA replication lagging strand
Tian, Congcong
Zhang, Qin
Jia, Jing
Zhou, Jiaqi
Zhang, Ziwei
Karri, Srinivasu
Jiang, Jiuhang
Dickinson, Quinn
Yao, Yuan
Tang, Xiaorong
Huang, Yuxin
Guo, Ting
He, Ziwei
Liu, Zheng
Gao, Yuan
Yang, Xinran
Wu, Yuchun
Chan, Kui Ming
Zhang, Daoqin
Han, Junhong
Yu, Chuanhe
Gan, Haiyun
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2024, 121 (20)
[44] Evolutionary conservation of residues in vertebrate DNA polymerase N conferring low fidelity and bypass activity
Takata, Kei-ichi
Arana, Mercedes E.
Seki, Mineaki
Kunkel, Thomas A.
Wood, Richard D.
NUCLEIC ACIDS RESEARCH, 2010, 38 (10) : 3233 - 3244
[45] Double domain fusion improves the reverse transcriptase activity and inhibitor tolerance of Bst DNA polymerase
Xiang, Rong
Liu, Guang-Yi
Hou, Yi
Xie, Long-Xu
Wang, Qing-Song
Hu, Song-Qing
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 274
[46] 5-O-Acyl plumbagins inhibit DNA polymerase activity and suppress the inflammatory response
Onodera, Takefumi
Kuriyama, Isoko
Sakamoto, Yuka
Kawamura, Moe
Kuramochi, Kouji
Tsubaki, Kazunori
Tabata, Atsushi
Naganune, Hideaki
Mizushina, Yoshiyuki
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2015, 573 : 100 - 110
[47] TRICHOMONAS-VAGINALIS - REPEATED DNA TARGET FOR HIGHLY SENSITIVE AND SPECIFIC POLYMERASE CHAIN-REACTION DIAGNOSIS
KENGNE, P
VEAS, F
VIDAL, N
REY, JL
CUNY, G
CELLULAR AND MOLECULAR BIOLOGY, 1994, 40 (06) : 819 - 831
[48] Building Fluorescent DNA Nanodevices on Target Living Cell Surfaces
Zhu, Guizhi
Zhang, Shengfeng
Song, Erqun
Zheng, Jing
Hu, Rong
Fang, Xiaohong
Tan, Weihong
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013, 52 (21) : 5490 - 5496
[49] Tailoring DNA Structure To Increase Target Hybridization Kinetics on Surfaces
Prigodich, Andrew E.
Lee, One-Sun
Daniel, Weston L.
Seferos, Dwight S.
Schatz, George C.
Mirkin, Chad A.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 132 (31) : 10638 - 10641
[50] Target search on a dynamic DNA molecule
Schoetz, Thomas
Neher, Richard A.
Gerland, Ulrich
PHYSICAL REVIEW E, 2011, 84 (05):

← 1 2 3 4 5 →