Bioactive Constituents from the Aerial Parts of Lippia triphylla

被引：27

作者：

Zhang, Yi ^{[1
]}

Chen, Yue ^{[1
]}

Wang, Shiyu ^{[2
]}

Dong, Yongzhe ^{[1
]}

Wang, Tingting ^{[2
]}

Qu, Lu ^{[1
]}

Li, Nan ^{[2
]}

Wang, Tao ^{[2
]}

机构：

[1] Tianjin State Key Lab Modern Chinese Med, Tianjin 300193, Peoples R China

[2] Tianjin Univ Tradit Chinese Med, Inst Tradit Chinese Med, Tianjin Key Lab TCM Chem & Anal, Tianjin 300193, Peoples R China

来源：

MOLECULES | 2015年 / 20卷 / 12期

关键词：

Lippia triphylla; lippianoside; structure elucidation; antioxidant; triglyceride accumulation inhibition; L6; cells; HepG2; CHINESE NATURAL MEDICINES; GLYCOSIDES; GLUCOSIDES; LIGNAN; ESTERS; LEAVES; LIVER;

D O I：

10.3390/molecules201219814

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Five new compounds, lippianosides A (1), B (2), C (3), D (4), and E (5), along with 26 (6-31) known ones were obtained from the 95% EtOH extract of Lippia triphylla (L. triphylla) aerial parts collected from Rwanda, Africa. Among the known compounds, 11 and 17-30 were isolated from the Lippia genus for the first time. In addition, 12, 13, and 16 were firstly obtained from this species. The structures of them were elucidated by chemical and spectroscopic methods. The antioxidant and triglyceride accumulation inhibition effects of the 31 compounds were examined in L6 cells and HepG2 cells, respectively.

引用

页码：21946 / 21959

页数：14

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