Azoospermia and 45,X/46,XY chromosomal mosaicism: A case report

被引：0
作者：
Le Chatton, M. [1 ]
Zaccabri, A. [2 ]
Agopiantz, M. [3 ]
Leheup, B. [4 ]
Weryha, G. [3 ]
Foliguet, B. [1 ,2 ]
机构：
[1] Maternite Reg Univ Nancy, Lab Biol Reprod, Univ Lorraine, F-54000 Nancy, France
[2] Maternite Reg Univ Nancy, Assistance Med Procreat, F-54000 Nancy, France
[3] CHU Nancy, Serv Endocrinol & Gynecol Med, F-54000 Nancy, France
[4] CHU Nancy, Serv Med Infantile & Genet Clin, F-54000 Nancy, France
来源：
GYNECOLOGIE OBSTETRIQUE & FERTILITE | 2013年 / 41卷 / 03期
关键词：
Azoospermia; 45; X/46; XY; Infertility; Gonadal dysgenesis; PHENOTYPE;
D O I：
10.1016/j.gyobfe.2013.01.007
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Chromosomal abnormalities are common in patients with oligozoospermia or azoospermia. We report the case of a 32-year patient, with male phenotype, and without hormonal or morphological abnormalities, with a severely reduced spermatogenesis. It was revealed a 45,X/46,XY gonadal dysgenesis. We have reviewed the various problems inherent in the discovery of this rare gonadal dysgenesis, including genetic, cancer and fertility risks. (C) 2013 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：203 / 206
页数：4
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