Past, present, and future of microcarrier-based tissue engineering

被引：95
作者：
Li, Bingyan [1 ]
Wang, Xin [1 ]
Wang, Yu [1 ]
Gou, Wenlong [1 ]
Yuan, Xueling [1 ]
Peng, Jiang [1 ]
Guo, Quanyi [1 ]
Lu, Shibi [1 ]
机构：
[1] Chinese Peoples Liberat Army Gen Hosp, Inst Orthoped, Fuxing Rd 28, Beijing 100853, Peoples R China
来源：
JOURNAL OF ORTHOPAEDIC TRANSLATION | 2015年 / 3卷 / 02期
基金：
国家高技术研究发展计划(863计划); 中国国家自然科学基金;
关键词：
cell; improvement; microcarrier; microtissue; tissue engineering; HUMAN ARTICULAR CHONDROCYTES; ADVANCED PARKINSONS-DISEASE; PIGMENT EPITHELIAL-CELLS; VENOUS LEG ULCERS; PROGENITOR CELLS; STEM-CELLS; INTRASTRIATAL IMPLANTATION; EXTRACELLULAR MATRICES; GELATIN MICROCARRIERS; BOVINE CHONDROCYTES;
D O I：
10.1016/j.jot.2015.02.003
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
The top issue in tissue engineering is how to obtain more seed cells quickly and to preserve their characteristic morphology during in vitro expansion culture of cells. Microcarriers can help to amplify cell numbers and maintain the appropriate phenotype for tissue repair and restoration of function. In addition, microtissue with cell microcarriers can be used to repair diseased tissues or organs. This review introduces the materials used for, and classification of, microcarriers and the improvements in, and potential applications of, microtissues with cell microcarriers in tissue engineering. Copyright (C) 2015, The Authors. Published by Elsevier (Singapore) Pte Ltd.
引用
收藏
页码：51 / 57
页数：7
相关论文
共 62 条
  • [1] Chondrocyte-alginate constructs with or without TGF-β1 produces superior extracellular matrix expression than monolayer cultures
    Ab-Rahim, Sharaniza
    Selvaratnam, Lakshmi
    Raghavendran, Hanumantha Rao Balaji
    Kamarul, Tunku
    [J]. MOLECULAR AND CELLULAR BIOCHEMISTRY, 2013, 376 (1-2) : 11 - 20
  • [2] Bakay RAE, 2004, FRONT BIOSCI-LANDMRK, V9, P592
  • [3] Bardy J, 2013, TISSUE ENG PART C-ME, V19, P166, DOI [10.1089/ten.tec.2012.0146, 10.1089/ten.TEC.2012.0146]
  • [4] Proliferation, activity, and osteogenic differentiation of bone marrow stromal cells cultured on calcium titanium phosphate microspheres
    Barrias, CC
    Ribeiro, CC
    Lamghari, M
    Miranda, CS
    Barbosa, MA
    [J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2005, 72A (01): : 57 - 66
  • [5] Adhesion and proliferation of human osteoblastic cells seeded on injectable hydroxyapatite microspheres
    Barrias, CC
    Ribeiro, CC
    Barbosa, MA
    [J]. BIOCERAMICS, VOL 16, 2004, 254-2 : 877 - 880
  • [6] The cell based dressing with living allogenic keratinocytes in the treatment of foot ulcers: a case study
    Bayram, Y
    Deveci, M
    Imirzalioglu, N
    Soysal, Y
    Sengezer, M
    [J]. BRITISH JOURNAL OF PLASTIC SURGERY, 2005, 58 (07): : 988 - 996
  • [7] Redifferentiation of dedifferentiated human articular chondrocytes: comparison of 2D and 3D cultures
    Caron, M. M. J.
    Emans, P. J.
    Coolsen, M. M. E.
    Voss, L.
    Surtel, D. A. M.
    Cremers, A.
    van Rhijn, L. W.
    Welting, T. J. M.
    [J]. OSTEOARTHRITIS AND CARTILAGE, 2012, 20 (10) : 1170 - 1178
  • [8] Differential Effect of ECM Molecules on Re-Expression of Cartilaginous Markers in Near Quiescent Human Chondrocytes
    Chiu, Li-Hsuan
    Chen, Shih-Ching
    Wu, Kai-Chen
    Yang, Charng-Bin
    Fang, Chia-Lang
    Lai, Wen-Fu T.
    Tsai, Yu-Hui
    [J]. JOURNAL OF CELLULAR PHYSIOLOGY, 2011, 226 (08) : 1981 - 1988
  • [9] Taking cell-matrix adhesions to the third dimension
    Cukierman, E
    Pankov, R
    Stevens, DR
    Yamada, KM
    [J]. SCIENCE, 2001, 294 (5547) : 1708 - 1712
  • [10] Encapsulation of osteoblast seeded microcarriers into injectable, photopolymerizable three-dimensional scaffolds based on D,L-lactide and ε-caprolactone
    Declercq, HA
    Gorski, TL
    Tielens, SP
    Schacht, EH
    Cornelissen, MJ
    [J]. BIOMACROMOLECULES, 2005, 6 (03) : 1608 - 1614
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