Interaction of Local Anesthetics with KcsA K+ Channel: Tetramer Stability and Docking Simulations

被引：0
|
作者：
Gray, Noel W. [1 ]
Zhorov, Boris S. [2 ,3 ]
Moczydlowski, Edward [4 ]
机构：
[1] SUNY Upstate Med Univ, Syracuse, NY 13210 USA
[2] McMaster Univ, Hamilton, ON, Canada
[3] Russian Acad Sci, Sechenov Inst, St Petersburg 196140, Russia
[4] Sandia Natl Labs, Albuquerque, NM 87185 USA
来源：
BIOPHYSICAL JOURNAL | 2013年 / 104卷 / 02期
关键词：
D O I：
10.1016/j.bpj.2012.11.705
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
引用
收藏
页码：122A / 122A
页数：1
相关论文
共 50 条
  • [31] The cavity and pore helices the KcsA K+ channel:: Electrostatic stabilization of monovalent cations
    Roux, B
    MacKinnon, R
    SCIENCE, 1999, 285 (5424) : 100 - 102
  • [32] TBA block of the KcsA K+ channel does not alter the selectivity filter conformation
    Yohannan, Sarah J.
    Hu, Yue
    Zhou, Yufeng
    BIOPHYSICAL JOURNAL, 2007, : 346A - 346A
  • [33] Statistic thermodynamics of the selectivity of KcsA channel to Na+, K+ and Rb+ ions
    An, HL
    Zhan, Y
    Zhang, SH
    Zhao, TJ
    Liu, JW
    PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2005, 32 (02) : 168 - 172
  • [34] Functional role and affinity of inorganic cations in stabilizing the tetrameric structure of the KcsA K+ channel
    Krishnan, MN
    Bingham, JP
    Lee, SH
    Trombley, P
    Moczydlowski, E
    JOURNAL OF GENERAL PHYSIOLOGY, 2005, 126 (03): : 271 - 283
  • [35] A mutant KcsA K+ channel with altered conduction properties and selectivity filter ion distribution
    Zhou, M
    MacKinnon, R
    JOURNAL OF MOLECULAR BIOLOGY, 2004, 338 (04) : 839 - 846
  • [36] Modelling the effect of a GHz electric field on the dynamics of K+ ions in KcsA potassium channel
    Sajadi, M.
    Lohrasebi, A.
    Rafii-Tabar, H.
    MOLECULAR SIMULATION, 2014, 40 (05) : 399 - 407
  • [37] Simulations of scorpion toxins and their interaction with K+ channels
    Bemporad, D
    Grottesi, A
    Robertson, G
    Sansom, M
    BIOPHYSICAL JOURNAL, 2004, 86 (01) : 513A - 513A
  • [38] K+/Na+ selectivity of KcsA potassium channel analyzed by reference interaction site model (RISM) integral equation theory
    Cui, QZ
    Smith, VH
    CHEMICAL PHYSICS LETTERS, 2002, 365 (1-2) : 110 - 116
  • [39] Local reactivity of charybdotoxin, a K+ channel blocker
    Ireta, J
    Galván, M
    Cho, K
    Joannopoulos, JD
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (38) : 9771 - 9778
  • [40] Molecular docking study of the binding of aminopyridines within the K+ channel
    Caballero, Norma Angelica
    Melendez, Francisco Javier
    Nino, Alfonso
    Munoz-Caro, Camelia
    JOURNAL OF MOLECULAR MODELING, 2007, 13 (05) : 579 - 586
12345