Harnessing the Power of Eph/ephrin Biosemiotics for Theranostic Applications

被引：6
作者：
Hughes, Robert M. [1 ]
Virag, Jitka A., I [2 ]
机构：
[1] East Carolina Univ, Dept Chem, Sci & Technol Bldg,SZ564,East 5th St, Greenville, NC 27858 USA
[2] East Carolina Univ, Brody Sch Med, Dept Physiol, Warren Life Sci Bldg,LSB239,600 Moye Blvd, Greenville, NC 27834 USA
来源：
PHARMACEUTICALS | 2020年 / 13卷 / 06期
关键词：
Eph/ephrin; receptor tyrosine kinase; therapeutic target; smart drug; nanoparticles; liposomes; exosomes; RECEPTOR TYROSINE KINASE; EPH RECEPTORS; TARGETED DELIVERY; BREAST-CANCER; HEPATOCELLULAR-CARCINOMA; CARDIOMYOCYTE APOPTOSIS; IN-VITRO; CELLS; EXPRESSION; EPHRINB2;
D O I：
10.3390/ph13060112
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Comprehensive basic biological knowledge of the Eph/ephrin system in the physiologic setting is needed to facilitate an understanding of its role and the effects of pathological processes on its activity, thereby paving the way for development of prospective therapeutic targets. To this end, this review briefly addresses what is currently known and being investigated in order to highlight the gaps and possible avenues for further investigation to capitalize on their diverse potential.
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收藏
页码：1 / 17
页数：17
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